HXT5/YHR096C Summary Help

Standard Name HXT5 1
Systematic Name YHR096C
Feature Type ORF, Verified
Description Hexose transporter with moderate affinity for glucose; induced in the presence of non-fermentable carbon sources, induced by a decrease in growth rate, contains an extended N-terminal domain relative to other HXTs; HXT5 has a paralog, HXT3, that arose from the whole genome duplication (2, 3, 4, 5)
Name Description HeXose Transporter 1
Chromosomal Location
ChrVIII:296447 to 294669 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All HXT5 GO evidence and references
  View Computational GO annotations for HXT5
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 6 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
50 total interaction(s) for 49 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Affinity Capture-RNA: 2
  • Co-fractionation: 2
  • PCA: 24
  • Protein-RNA: 1
  • Two-hybrid: 2

Genetic Interactions
  • Negative Genetic: 9
  • Phenotypic Enhancement: 6
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 592
Molecular Weight (Da) 66,251
Isoelectric Point (pI) 7.51
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVIII:296447 to 294669 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1779 296447..294669 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB
Primary SGDIDS000001138
References cited on this page View Complete Literature Guide for HXT5
1) Reifenberger E, et al.  (1995) Identification of novel HXT genes in Saccharomyces cerevisiae reveals the impact of individual hexose transporters on glycolytic flux. Mol Microbiol 16(1):157-67
2) Diderich JA, et al.  (2001) Functional analysis of the hexose transporter homologue HXT5 in Saccharomyces cerevisiae. Yeast 18(16):1515-24
3) Verwaal R, et al.  (2002) HXT5 expression is determined by growth rates in Saccharomyces cerevisiae. Yeast 19(12):1029-38
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
5) Greatrix BW and van Vuuren HJ  (2006) Expression of the HXT13, HXT15 and HXT17 genes in Saccharomyces cerevisiae and stabilization of the HXT1 gene transcript by sugar-induced osmotic stress. Curr Genet 49(4):205-17