HXT2/YMR011W Summary Help

Standard Name HXT2 1
Systematic Name YMR011W
Feature Type ORF, Verified
Description High-affinity glucose transporter of the major facilitator superfamily; expression is induced by low levels of glucose and repressed by high levels of glucose (2, 3)
Name Description HeXose Transporter 1
Chromosomal Location
ChrXIII:288079 to 289704 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All HXT2 GO evidence and references
  View Computational GO annotations for HXT2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 12 genes
Resources
Classical genetics
null
Large-scale survey
null
unspecified
Resources
123 total interaction(s) for 96 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 1
  • Co-fractionation: 2
  • Co-purification: 1
  • PCA: 8
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Rescue: 4
  • Negative Genetic: 77
  • Phenotypic Enhancement: 7
  • Phenotypic Suppression: 1
  • Positive Genetic: 11
  • Synthetic Growth Defect: 4

Resources
Expression Summary
histogram
Resources
Length (a.a.) 541
Molecular Weight (Da) 59,840
Isoelectric Point (pI) 8.31
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:288079 to 289704 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1626 288079..289704 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB
Primary SGDIDS000004613
References cited on this page View Complete Literature Guide for HXT2
1) Kruckeberg AL and Bisson LF  (1990) The HXT2 gene of Saccharomyces cerevisiae is required for high-affinity glucose transport. Mol Cell Biol 10(11):5903-13
2) Ozcan S and Johnston M  (1999) Function and regulation of yeast hexose transporters. Microbiol Mol Biol Rev 63(3):554-69
3) Ozcan S and Johnston M  (1995) Three different regulatory mechanisms enable yeast hexose transporter (HXT) genes to be induced by different levels of glucose. Mol Cell Biol 15(3):1564-72