HMI1/YOL095C Summary Help

Standard Name HMI1 1
Systematic Name YOL095C
Feature Type ORF, Verified
Description Mitochondrial inner membrane localized ATP-dependent DNA helicase; required for the maintenance of the mitochondrial genome; not required for mitochondrial transcription; has homology to E. coli helicase uvrD (2, 3)
Name Description Helicase in MItochondria 1
Chromosomal Location
ChrXV:141347 to 139227 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All HMI1 GO evidence and references
  View Computational GO annotations for HMI1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Classical genetics
null
unspecified
Large-scale survey
null
overexpression
unspecified
Resources
128 total interaction(s) for 98 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • Affinity Capture-RNA: 1

Genetic Interactions
  • Negative Genetic: 106
  • Positive Genetic: 10
  • Synthetic Growth Defect: 3
  • Synthetic Lethality: 2
  • Synthetic Rescue: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 706
Molecular Weight (Da) 80,575
Isoelectric Point (pI) 8.93
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:141347 to 139227 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2006-01-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2121 141347..139227 2006-01-05 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005455
References cited on this page View Complete Literature Guide for HMI1
1) Lecrenier, N. and F. Foury  (1998) personal communication
2) Sedman T, et al.  (2000) A DNA helicase required for maintenance of the functional mitochondrial genome in Saccharomyces cerevisiae. Mol Cell Biol 20(5):1816-24
3) Lee CM, et al.  (1999) The DNA helicase, Hmi1p, is transported into mitochondria by a C-terminal cleavable targeting signal. J Biol Chem 274(30):20937-42