Standard Name	HHY1 1
Systematic Name	YEL059W
Feature Type	ORF, Dubious
Description	Dubious open reading frame unlikely to encode a functional protein; mutant is hypersensitive to hygromycin B indicative of defects in vacuolar trafficking (1, 2)
Name Description	Hypersensitivity to HYgromycin B 1

Chromosomal Location	ChrV:42652 to 42960 | ORF Map | GBrowse

	View Computational GO annotations for HHY1
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	biological_process unknown (ND)
Cellular Component
Manually curated	integral to membrane (ISM)

Retired Name	ENV6

Classical genetics
null	acid pH resistance: decreased alkaline pH resistance: decreased ionic stress resistance: decreased precursor carboxypeptidase Y secretion: abnormal precursor carboxypeptidase Y accumulation: increased resistance to sirolimus: decreased resistance to caffeine: decreased resistance to monensin: decreased vacuolar morphology: abnormal
Large-scale survey
null	anaerobic growth: decreased bud morphology: abnormal competitive fitness: decreased haploproficient heat sensitivity: increased Fus-Mid-GFP distribution: abnormal resistance to (S)-lactic acid: decreased resistance to sirolimus: decreased resistance to caffeine: decreased resistance to hydroxyurea: decreased resistance to camptothecin: decreased resistance to CTBT: decreased resistance to hygromycin B: decreased resistance to nickel sulfate: increased resistance to sodium selenide: decreased resistance to wortmannin: normal resistance to methyl methanesulfonate: decreased resistance to hydrogen chloride: decreased resistance to acetic acid: decreased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrV:42652 to 42960 | ORF Map | GBrowse
Last Update	Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..309 42652..42960 1996-07-31 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain CLIB382 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000785