HED1/YDR014W-A Summary Help

Standard Name HED1 1
Systematic Name YDR014W-A
Feature Type ORF, Verified
Description Meiosis-specific protein; down-regulates Rad51p-mediated mitotic recombination when the meiotic recombination machinery is impaired; prevents the recruitment of Rad54p to site-specific DNA double-strand breaks in vivo; early meiotic gene, transcribed specifically during meiotic prophase (1, 2)
Name Description High copy suppressor of rED1 1
Chromosomal Location
ChrIV:477797 to 478285 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All HED1 GO evidence and references
  View Computational GO annotations for HED1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
13 total interaction(s) for 6 unique genes/features.
Physical Interactions
  • Reconstituted Complex: 3
  • Two-hybrid: 6

Genetic Interactions
  • Dosage Rescue: 1
  • Phenotypic Enhancement: 1
  • Synthetic Rescue: 2

Resources
Length (a.a.) 162
Molecular Weight (Da) 18,258
Isoelectric Point (pI) 10.84
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:477797 to 478285 | ORF Map | GBrowse
This feature contains embedded feature(s): YDR015C
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2006-04-14
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..489 477797..478285 2011-02-03 2006-04-14
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000113613
References cited on this page View Complete Literature Guide for HED1
1) Tsubouchi H and Roeder GS  (2006) Budding yeast Hed1 down-regulates the mitotic recombination machinery when meiotic recombination is impaired. Genes Dev 20(13):1766-75
2) Busygina V, et al.  (2008) Hed1 regulates Rad51-mediated recombination via a novel mechanism. Genes Dev 22(6):786-95