HBN1/YCL026C-B Summary Help

Standard Name HBN1 1
Systematic Name YCL026C-B
Alias YCL027C-A
Feature Type ORF, Verified
Description Protein of unknown function; similar to bacterial nitroreductases; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; protein becomes insoluble upon intracellular iron depletion; protein abundance increases in response to DNA replication stress (1, 2, 3, 4)
Name Description Homologous to Bacterial Nitroreductases 1
Chromosomal Location
ChrIII:73986 to 73405 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All HBN1 GO evidence and references
  View Computational GO annotations for HBN1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 6 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
6 total interaction(s) for 5 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 2

Genetic Interactions
  • Phenotypic Enhancement: 3
  • Synthetic Growth Defect: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 193
Molecular Weight (Da) 20,994
Isoelectric Point (pI) 6.98
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIII:73986 to 73405 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2000-09-14 | Sequence: 2000-09-14
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..582 73986..73405 2000-09-14 2000-09-14
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000007548
References cited on this page View Complete Literature Guide for HBN1
1) de Oliveira IM, et al.  (2007) In silico identification of a new group of specific bacterial and fungal nitroreductases-like proteins. Biochem Biophys Res Commun 355(4):919-25
2) Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
3) Seo HY, et al.  (2008) Proteomic Analysis of Recombinant Saccharomyces cerevisiae Upon Iron Deficiency Induced via Human H-Ferritin Production. J Microbiol Biotechnol 18(8):1368-76
4) Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76