GYP7/YDL234C Summary Help

Standard Name GYP7 1
Systematic Name YDL234C
Feature Type ORF, Verified
Description GTPase-activating protein for yeast Rab family members; members include Ypt7p (most effective), Ypt1p, Ypt31p, and Ypt32p (in vitro); involved in vesicle mediated protein trafficking (1, 2, 3)
Name Description Gtpase-activating protein for Ypt7 Protein 1
Chromosomal Location
ChrIV:36477 to 34237 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All GYP7 GO evidence and references
  View Computational GO annotations for GYP7
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 10 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
overexpression
Resources
27 total interaction(s) for 24 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • Affinity Capture-RNA: 1

Genetic Interactions
  • Dosage Growth Defect: 1
  • Negative Genetic: 14
  • Phenotypic Suppression: 2
  • Positive Genetic: 3
  • Synthetic Growth Defect: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 746
Molecular Weight (Da) 87,305
Isoelectric Point (pI) 4.88
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:36477 to 34237 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2241 36477..34237 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002393
References cited on this page View Complete Literature Guide for GYP7
1) Vollmer P, et al.  (1999) Primary structure and biochemical characterization of yeast GTPase-activating proteins with substrate preference for the transport GTPase Ypt7p. Eur J Biochem 260(1):284-90
2) Eitzen G, et al.  (2000) Sequential action of two GTPases to promote vacuole docking and fusion. EMBO J 19(24):6713-20
3) Eitzen G, et al.  (2001) Rho1p and Cdc42p act after Ypt7p to regulate vacuole docking. EMBO J 20(20):5650-6