GSP2/YOR185C Summary Help

GSP2 BASIC INFORMATION

Standard Name GSP2
Systematic Name YOR185C
Alias CNR2 1
Feature Type ORF, Verified
Description GTP binding protein (mammalian Ranp homolog) involved in the maintenance of nuclear organization, RNA processing and transport; interacts with Kap121p, Kap123p and Pdr6p (karyophilin betas); Gsp1p homolog that is not required for viability (2, 3)
Name Description Genetic Suppressor of Prp20-1 2
GO Annotations All GSP2 GO evidence and references
    View Computational GO annotations for GSP2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All GSP2 Phenotype details and references
Large-scale survey
null
overexpression
Interactions GSP2 All interactions details and references
38 total interaction(s) for 30 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 20
  • Affinity Capture-RNA: 1
  • Two-hybrid: 9
Genetic Interactions
  • Dosage Rescue: 4
  • Phenotypic Enhancement: 2
  • Phenotypic Suppression: 2
Sequence Information
ChrXV:682107 to 681445 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: 98.6 cM
Last Update Coordinates: 2006-01-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..663 682107..681445 2006-01-05 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000005711

GSP2 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
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  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
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  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for GSP2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for GSP2]

1) Kadowaki T, et al.  (1993) Regulation of RNA processing and transport by a nuclear guanine nucleotide release protein and members of the Ras superfamily. EMBO J 12(7):2929-37
2) Belhumeur P, et al.  (1993) GSP1 and GSP2, genetic suppressors of the prp20-1 mutant in Saccharomyces cerevisiae: GTP-binding proteins involved in the maintenance of nuclear organization. Mol Cell Biol 13(4):2152-61
3) Lau D, et al.  (2000) Purification of protein A-tagged yeast ran reveals association with a novel karyopherin beta family member, Pdr6p. J Biol Chem 275(1):467-71