GPI13/YLL031C Summary Help

Standard Name GPI13 1
Systematic Name YLL031C
Alias MPC1 2
Feature Type ORF, Verified
Description ER membrane localized phosphoryltransferase; adds phosphoethanolamine onto the third mannose residue of the glycosylphosphatidylinositol (GPI) anchor precursor; similar to human PIG-O protein (1, 3)
Name Description GlycosylPhosphatidylInositol anchor biosynthesis 1
Chromosomal Location
ChrXII:80205 to 77152 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All GPI13 GO evidence and references
  View Computational GO annotations for GPI13
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 2 genes
Resources
Classical genetics
null
Large-scale survey
null
reduction of function
Resources
40 total interaction(s) for 36 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 2
  • Co-purification: 1
  • PCA: 2
  • Protein-RNA: 1

Genetic Interactions
  • Dosage Growth Defect: 1
  • Dosage Rescue: 9
  • Negative Genetic: 13
  • Positive Genetic: 2
  • Synthetic Growth Defect: 4
  • Synthetic Lethality: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,017
Molecular Weight (Da) 115,633
Isoelectric Point (pI) 6.62
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:80205 to 77152 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..3054 80205..77152 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003954
References cited on this page View Complete Literature Guide for GPI13
1) Taron CH, et al.  (2000) Glycosylphosphatidylinositol biosynthesis defects in Gpi11p- and Gpi13p-deficient yeast suggest a branched pathway and implicate gpi13p in phosphoethanolamine transfer to the third mannose. Mol Biol Cell 11(5):1611-30
2) Tohe A and Oguchi T  (2000) An improved integration replacement/disruption method for mutagenesis of yeast essential genes. Genes Genet Syst 75(1):33-9
3) Flury I, et al.  (2000) YLL031c belongs to a novel family of membrane proteins involved in the transfer of ethanolaminephosphate onto the core structure of glycosylphosphatidylinositol anchors in yeast. J Biol Chem 275(32):24458-65