GOT1/YMR292W Summary Help

Standard Name GOT1 1
Systematic Name YMR292W
Feature Type ORF, Verified
Description Homodimeric protein that is packaged into COPII vesicles; cycles between the ER and Golgi; involved in secretory transport but not directly required for aspects of transport assayed in vitro; may influence membrane composition (1, 2)
Name Description GOlgi Transport 1
Chromosomal Location
ChrXIII:854795 to 855293 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All GOT1 GO evidence and references
  View Computational GO annotations for GOT1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 4 genes
Resources
Classical genetics
overexpression
Large-scale survey
null
Resources
119 total interaction(s) for 55 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 1
  • PCA: 16

Genetic Interactions
  • Dosage Lethality: 1
  • Dosage Rescue: 2
  • Negative Genetic: 60
  • Phenotypic Enhancement: 22
  • Phenotypic Suppression: 7
  • Positive Genetic: 4
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 138
Molecular Weight (Da) 15,431
Isoelectric Point (pI) 11.34
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:854795 to 855293 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..22 854795..854816 2011-02-03 1996-07-31
Intron 23..104 854817..854898 2011-02-03 1996-07-31
CDS 105..499 854899..855293 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004906
References cited on this page View Complete Literature Guide for GOT1
1) Conchon S, et al.  (1999) Got1p and Sft2p: membrane proteins involved in traffic to the Golgi complex. EMBO J 18(14):3934-46
2) Lorente-Rodriguez A, et al.  (2009) Multicopy suppressor analysis of thermosensitive YIP1 alleles implicates GOT1 in transport from the ER. J Cell Sci 122(Pt 10):1540-50