Standard Name	GOS1
Systematic Name	YHL031C
Feature Type	ORF, Verified
Description	v-SNARE protein involved in Golgi transport, homolog of the mammalian protein GOS-28/GS28 (1)
Name Description	GOlgi Snare 2

Chromosomal Location	ChrVIII:39486 to 38815 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for GOS1
Molecular Function
Manually curated	SNAP receptor activity (IDA)
Biological Process
Manually curated	Golgi vesicle transport (IMP) vesicle fusion (IDA)
Cellular Component
Manually curated	Golgi medial cisterna (IDA) integral to membrane (ISS, NAS) SNARE complex (IDA)

Classical genetics
null	chronological lifespan: increased
overexpression	resistance to hydroxyurea: decreased
Large-scale survey
null	UV resistance: decreased acid pH resistance: decreased rubidium(1+) accumulation: decreased polyphosphate accumulation: abnormal glutathione excretion: increased competitive fitness: decreased haploinsufficient heat sensitivity: increased metal resistance: decreased Can1p-GFP distribution: abnormal resistance to cycloheximide: increased resistance to camptothecin: increased resistance to nickel sulfate: increased resistance to cycloheximide: decreased resistance to amitrole: decreased resistance to sirolimus: decreased resistance to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO): decreased resistance to quinine: decreased resistance to tunicamycin: decreased resistance to 1,4-dithiothreitol: decreased resistance to hygromycin B: decreased resistance to spermine: decreased resistance to bleomycin: decreased resistance to caffeine: decreased resistance to mycophenolic acid: decreased resistance to dimethyl sulfoxide: decreased resistance to ciclopirox olamine: decreased resistance to clioquinol: decreased resistance to wortmannin: normal resistance to tunicamycin: increased toxin resistance: decreased vacuolar morphology: abnormal viable
overexpression	cell cycle progression in G1 phase: abnormal vegetative growth: decreased vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	246 total interaction(s) for 132 unique genes/features.
Physical Interactions	Affinity Capture-MS: 2 Affinity Capture-RNA: 2 Affinity Capture-Western: 11 Co-fractionation: 1 Co-localization: 1 Co-purification: 2 Reconstituted Complex: 14 Two-hybrid: 2
Genetic Interactions	Dosage Growth Defect: 3 Dosage Lethality: 3 Dosage Rescue: 2 Negative Genetic: 130 Phenotypic Enhancement: 28 Phenotypic Suppression: 17 Positive Genetic: 5 Synthetic Growth Defect: 13 Synthetic Lethality: 8 Synthetic Rescue: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrVIII:39486 to 38815 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..672 39486..38815 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001023