GON7/YJL184W Summary

GON7 BASIC INFORMATION

Standard Name	GON7 1
Systematic Name	YJL184W
Alias	LDB6 1 , PCC2 2
Feature Type	ORF, Verified
Description	Protein proposed to be involved in the modification of N-linked oligosaccharides, osmotic stress response, telomere uncapping and elongation, transcription; component of the EKC/KEOPS protein complex with Kae1p, Cgi121p, Pcc1p, and Bud32p (1, 2, 3, 4)

GO Annotations	All GON7 GO evidence and references
	View Computational GO annotations for GON7
Molecular Function
Manually curated	chromatin DNA binding (IDA)
Biological Process
Manually curated	cell wall mannoprotein biosynthetic process (IMP) positive regulation of transcription from RNA polymerase II promoter (IPI) telomere maintenance (IMP)
Cellular Component
Manually curated	EKC/KEOPS protein complex (IDA) colocalizes_with nuclear chromatin (IDA)

Mutant Phenotype	All GON7 Phenotype details and references
Classical genetics
null	metal resistance: decreased
Large-scale survey
null	bud morphology: abnormal competitive fitness: decreased inviable oxidative stress resistance: decreased resistance to L-1,4-dithiothreitol: decreased resistance to oleate: decreased resistance to oxalic acid: decreased resistance to amiodarone: decreased resistance to doxorubicin: decreased resistance to glucose: decreased respiratory growth: absent utilization of nitrogen source: absent viable

Interactions	GON7 All interactions details and references
	View additional details at BioGRID
	25 total interaction(s) for 15 unique genes/features.
Physical Interactions	Affinity Capture-MS: 10 Affinity Capture-RNA: 1 Affinity Capture-Western: 1 Biochemical Activity: 1 Two-hybrid: 4
Genetic Interactions	Negative Genetic: 2 Positive Genetic: 2 Synthetic Growth Defect: 3 Synthetic Lethality: 1

Sequence Information

ChrX:83446 to 83817 | |

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..372	83446..83817	1996-07-31	1996-07-31

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000003720

GON7 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for GON7

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for GON7]

1)	Corbacho I, et al. (2004) Identification of low-dye-binding (ldb) mutants of Saccharomyces cerevisiae. FEMS Yeast Res 4(4-5):437-44
2)	Kisseleva-Romanova E, et al. (2006) Yeast homolog of a cancer-testis antigen defines a new transcription complex. EMBO J 25(15):3576-85
3)	Garay-Arroyo A, et al. (2000) Highly hydrophilic proteins in prokaryotes and eukaryotes are common during conditions of water deficit. J Biol Chem 275(8):5668-74
4)	Downey M, et al. (2006) A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator. Cell 124(6):1155-68

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