GLY1/YEL046C Summary Help

Standard Name GLY1
Systematic Name YEL046C
Feature Type ORF, Verified
Description Threonine aldolase; catalyzes the cleavage of L-allo-threonine and L-threonine to glycine; involved in glycine biosynthesis (1, 2)
Name Description GLYcine requiring
Chromosomal Location
ChrV:68792 to 67629 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All GLY1 GO evidence and references
  View Computational GO annotations for GLY1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 9 genes
Resources
Pathways
Classical genetics
null
Large-scale survey
null
overexpression
Resources
40 total interaction(s) for 30 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 18
  • Affinity Capture-RNA: 7
  • Affinity Capture-Western: 3
  • PCA: 1

Genetic Interactions
  • Dosage Rescue: 1
  • Phenotypic Suppression: 2
  • Synthetic Growth Defect: 5
  • Synthetic Lethality: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 387
Molecular Weight (Da) 42,815
Isoelectric Point (pI) 6.24
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrV:68792 to 67629 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1164 68792..67629 1996-07-31 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000772
References cited on this page View Complete Literature Guide for GLY1
1) Liu JQ, et al.  (1997) The GLY1 gene of Saccharomyces cerevisiae encodes a low-specific L-threonine aldolase that catalyzes cleavage of L-allo-threonine and L-threonine to glycine--expression of the gene in Escherichia coli and purification and characterization of the enzyme. Eur J Biochem 245(2):289-93
2) Monschau N, et al.  (1997) Identification of Saccharomyces cerevisiae GLY1 as a threonine aldolase: a key enzyme in glycine biosynthesis. FEMS Microbiol Lett 150(1):55-60