| Standard Name | GIR2 |
|---|---|
| Systematic Name | YDR152W |
| Feature Type | ORF, Verified |
| Description | Highly-acidic cytoplasmic RWD domain-containing protein of unknown function; forms a complex with Rbg2p; interacts with Rbg1p and Gcn1p; associates with translating ribosomes; putative intrinsically unstructured protein (1, 2, 3, 4) |
| Name Description | Genetically Interacts with Ribosomal genes 3 |
| Chromosomal Location | |
|---|---|
Gene Ontology Annotations All GIR2 GO evidence and references
| Molecular Function | |
|---|---|
| Manually curated |
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| Biological Process | |
| Manually curated | |
| Cellular Component | |
| Manually curated | |
| High-throughput |
Mutant phenotypes All GIR2 Phenotype evidence and references
| Classical genetics | |
|---|---|
| overexpression | |
| Large-scale survey | |
| null |
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| Resources |
interactions All GIR2 Interaction evidence and references
| 45 total interaction(s) for 31 unique genes/features. | |
| Physical Interactions |
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| Genetic Interactions |
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| Resources |
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Expression Summary
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| Resources |
Protein Information All GIR2 Protein evidence and references
| Localization | |
|---|---|
| Phosphorylation | PhosphoGRID | PhosphoPep Database |
| Structure | |
| Homologs |
sequence information
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| Last Update | Coordinates: 2011-02-03 | Sequence: 1996-07-31 | ||||||||||||
| Subfeature details |
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| Retrieve sequences | |||||||||||||
Analyze Sequence
| S288C only | |
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| S288C vs. other species | |
| S288C vs. other strains |
Resources
| External Links | All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB |
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| Primary SGDID | S000002559 |
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References cited on this page View Complete Literature Guide for GIR2
| 1) | Alves VS, et al. (2004) Biophysical characterization of Gir2, a highly acidic protein of Saccharomyces cerevisiae with anomalous electrophoretic behavior. Biochem Biophys Res Commun 314(1):229-34 |
| 2) | Alves VS and Castilho BA (2005) Gir2 is an intrinsically unstructured protein that is present in Saccharomyces cerevisiae as a group of heterogeneously electrophoretic migrating forms. Biochem Biophys Res Commun 332(2):450-5 |
| 3) | Wout PK, et al. (2009) Saccharomyces cerevisiae Rbg1 protein and its binding partner Gir2 interact on Polyribosomes with Gcn1. Eukaryot Cell 8(7):1061-71 |
| 4) | Daugeron MC, et al. (2011) The highly conserved eukaryotic DRG factors are required for efficient translation in a manner redundant with the putative RNA helicase Slh1. Nucleic Acids Res 39(6):2221-33 |




