Standard Name	GGC1 1 (see Nomenclature conflict Note)
Systematic Name	YDL198C
Alias	YHM1 2 , SHM1 3
Feature Type	ORF, Verified
Description	Mitochondrial GTP/GDP transporter, essential for mitochondrial genome maintenance; has a role in mitochondrial iron transport; member of the mitochondrial carrier family (2)
Name Description	GDP/GTP Carrier 1

Chromosomal Location	ChrIV:104551 to 103649 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for GGC1
Molecular Function
Manually curated	guanine nucleotide transmembrane transporter activity (IDA)
Biological Process
Manually curated	cellular iron ion homeostasis (IMP) guanine nucleotide transport (IDA) mitochondrial genome maintenance (IGI, IMP) transmembrane transport (IDA)
Cellular Component
Manually curated	mitochondrial inner membrane (ISS)
High-throughput	integral to membrane (ISM) mitochondrion (IDA)

Classical genetics
null	resistance to sirolimus: increased
Large-scale survey
null	bud morphology: abnormal glycogen accumulation: decreased competitive fitness: decreased heat sensitivity: increased resistance to sirolimus: increased resistance to doxorubicin: decreased resistance to oleate: decreased resistance to ethanol: decreased resistance to 2,4-dichlorophenol: decreased resistance to sodium selenide: decreased resistance to wortmannin: normal resistance to elesclomol-Cu: decreased respiratory growth: absent respiratory growth: decreased rate stress resistance: increased toxin resistance: increased toxin resistance: decreased utilization of carbon source: decreased utilization of nitrogen source: absent vacuolar morphology: abnormal vegetative growth: decreased rate viable
overexpression	vegetative growth: decreased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	23 total interaction(s) for 19 unique genes/features.
Physical Interactions	Affinity Capture-MS: 4 Biochemical Activity: 2 PCA: 6
Genetic Interactions	Dosage Lethality: 1 Dosage Rescue: 1 Phenotypic Enhancement: 3 Synthetic Growth Defect: 3 Synthetic Lethality: 3
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIV:104551 to 103649 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..903 104551..103649 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000002357