GGA1/YDR358W Summary Help

Standard Name GGA1 1
Systematic Name YDR358W
Feature Type ORF, Verified
Description Golgi-localized protein with homology to gamma-adaptin; interacts with and regulates Arf1p and Arf2p in a GTP-dependent manner in order to facilitate traffic through the late Golgi; GGA1 has a paralog, GGA2, that arose from the whole genome duplication (1, 2)
Name Description Golgi-localized, Gamma-adaptin ear homology, Arf-binding protein 1
Chromosomal Location
ChrIV:1190059 to 1191732 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All GGA1 GO evidence and references
  View Computational GO annotations for GGA1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 3 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
97 total interaction(s) for 62 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 5
  • Co-crystal Structure: 1
  • Reconstituted Complex: 1
  • Two-hybrid: 5

Genetic Interactions
  • Negative Genetic: 54
  • Phenotypic Enhancement: 6
  • Phenotypic Suppression: 1
  • Positive Genetic: 3
  • Synthetic Growth Defect: 8
  • Synthetic Lethality: 7
  • Synthetic Rescue: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 557
Molecular Weight (Da) 62,319
Isoelectric Point (pI) 5.36
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:1190059 to 1191732 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1674 1190059..1191732 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002766
References cited on this page View Complete Literature Guide for GGA1
1) Zhdankina O, et al.  (2001) Yeast GGA proteins interact with GTP-bound Arf and facilitate transport through the Golgi. Yeast 18(1):1-18
2) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61