Standard Name	GFD1
Systematic Name	YMR255W
Feature Type	ORF, Verified
Description	Coiled-coiled protein of unknown function; identified as a high-copy suppressor of a dbp5 mutation; protein abundance increases in response to DNA replication stress (1, 2)
Name Description	Good For Dbp5p 1

Chromosomal Location	ChrXIII:778001 to 778567 | ORF Map | GBrowse

	View Computational GO annotations for GFD1
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	mRNA export from nucleus (IGI)
Cellular Component
Manually curated	cytoplasm (IDA) nuclear pore (IDA)
High-throughput	integral to membrane (ISM)

Large-scale survey
null	competitive fitness: decreased resistance to bleomycin: increased resistance to methyl methanesulfonate: increased resistance to paromomycin: decreased resistance to cycloheximide: decreased resistance to benzo[a]pyrene: decreased resistance to camptothecin: increased resistance to fenpropimorph: decreased resistance to hydroxyurea: increased sporulation efficiency: increased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	57 total interaction(s) for 31 unique genes/features.
Physical Interactions	Affinity Capture-MS: 5 Affinity Capture-RNA: 4 Affinity Capture-Western: 1 Co-crystal Structure: 1 PCA: 1 Reconstituted Complex: 8 Two-hybrid: 12
Genetic Interactions	Dosage Rescue: 5 Negative Genetic: 7 Positive Genetic: 9 Synthetic Growth Defect: 2 Synthetic Lethality: 1 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXIII:778001 to 778567 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..567 778001..778567 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004868