Standard Name	GDI1
Systematic Name	YER136W
Alias	SEC19 1
Feature Type	ORF, Verified
Description	GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by regulating the dissociation of GDP from the Sec4/Ypt/rab family of GTP binding proteins (2, 3)
Name Description	GDP Dissociation Inhibitor

Chromosomal Location	ChrV:439616 to 440971 | ORF Map | GBrowse

	View Computational GO annotations for GDI1
Molecular Function
Manually curated	Rab GDP-dissociation inhibitor activity (IDA)
Biological Process
Manually curated	vesicle-mediated transport (IMP)
Cellular Component
Manually curated	cellular_component unknown (ND)

Classical genetics
conditional	endomembrane system morphology: abnormal endoplasmic reticulum morphology: abnormal invertase secretion: decreased invertase accumulation: increased
Large-scale survey
null	haploinsufficient inviable
overexpression	vegetative growth: decreased rate
Resources	PROPHECY | PhenoM | SCMD | ScreenTroll | Yeast Fitness Database

	97 total interaction(s) for 34 unique genes/features.
Physical Interactions	Affinity Capture-MS: 32 Affinity Capture-RNA: 2 Affinity Capture-Western: 7 Co-crystal Structure: 4 PCA: 10 Reconstituted Complex: 1 Two-hybrid: 23
Genetic Interactions	Dosage Lethality: 1 Dosage Rescue: 2 Phenotypic Suppression: 1 Positive Genetic: 2 Synthetic Lethality: 12
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrV:439616 to 440971 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1356 439616..440971 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000938