GDI1/YER136W Summary Help

Standard Name GDI1 1
Systematic Name YER136W
Alias SEC19 2
Feature Type ORF, Verified
Description GDP dissociation inhibitor; regulates vesicle traffic in secretory pathways by regulating the dissociation of GDP from the Sec4/Ypt/rab family of GTP binding proteins (1, 3)
Name Description GDP Dissociation Inhibitor 1
Chromosomal Location
ChrV:439616 to 440971 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All GDI1 GO evidence and references
  View Computational GO annotations for GDI1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 5 genes
Resources
Classical genetics
conditional
Large-scale survey
null
overexpression
Resources
101 total interaction(s) for 36 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 34
  • Affinity Capture-RNA: 4
  • Affinity Capture-Western: 7
  • Co-crystal Structure: 4
  • PCA: 10
  • Reconstituted Complex: 1
  • Two-hybrid: 23

Genetic Interactions
  • Dosage Lethality: 1
  • Dosage Rescue: 2
  • Phenotypic Suppression: 1
  • Positive Genetic: 2
  • Synthetic Lethality: 12

Resources
Expression Summary
histogram
Resources
Length (a.a.) 451
Molecular Weight (Da) 51,206
Isoelectric Point (pI) 5.87
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrV:439616 to 440971 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1356 439616..440971 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000938
References cited on this page View Complete Literature Guide for GDI1
1) Garrett MD, et al.  (1994) GDI1 encodes a GDP dissociation inhibitor that plays an essential role in the yeast secretory pathway. EMBO J 13(7):1718-28
2) Novick P, et al.  (1980) Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway. Cell 21(1):205-15
3) Collins RN, et al.  (1997) Interactions of nucleotide release factor Dss4p with Sec4p in the post-Golgi secretory pathway of yeast. J Biol Chem 272(29):18281-9