GDA1/YEL042W Summary

GDA1 BASIC INFORMATION

Standard Name	GDA1
Systematic Name	YEL042W
Feature Type	ORF, Verified
Description	Guanosine diphosphatase located in the Golgi, involved in the transport of GDP-mannose into the Golgi lumen by converting GDP to GMP after mannose is transferred its substrate (1)
Name Description	Guanosine DiphosphatAse

GO Annotations	All GDA1 GO evidence and references
	View Computational GO annotations for GDA1
Molecular Function
Manually curated	guanosine-diphosphatase activity (IDA) uridine-diphosphatase activity (IDA)
Biological Process
Manually curated	protein amino acid glycosylation (TAS)
Cellular Component
Manually curated	Golgi apparatus (TAS)

Mutant Phenotype	All GDA1 Phenotype details and references
Classical genetics
null	toxin resistance: decreased
Large-scale survey
null	glycogen accumulation: increased competitive fitness: decreased resistance to ethanol: decreased toxin resistance: decreased viable

Interactions	GDA1 All interactions details and references
	136 total interaction(s) for 77 unique genes/features.
Physical Interactions	Affinity Capture-MS: 2 Biochemical Activity: 1 Two-hybrid: 6
Genetic Interactions	Dosage Rescue: 1 Phenotypic Enhancement: 109 Phenotypic Suppression: 13 Synthetic Lethality: 1 Synthetic Rescue: 3

Sequence Information

ChrV:73771 to 75327 | |

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1557	73771..75327	1996-07-31	1996-07-31

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000000768

GDA1 RESOURCES

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SGD ORF map	GBrowse

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Expression Summary

ADDITIONAL INFORMATION for GDA1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for GDA1]

1)	Berninsone P, et al. (1994) The Golgi guanosine diphosphatase is required for transport of GDP-mannose into the lumen of Saccharomyces cerevisiae Golgi vesicles. J Biol Chem 269(1):207-11

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