Search results for Locus Summary pages at SGD

Your query, G2, returned 70 hits to the following gene names:

Match Gene Name Systematic Name Alias(es) Position Info Description
AFG2 AFG2 YLR397C DRG1, AAA family ATPase AFG2

ChrXII:914892 to 912550 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2343 914892..912550

ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex; is essential for pre-60S maturation and release of several preribosome maturation factors; releases Rlp24p from purified pre-60S particles in vitro; target of the ribosomal biosynthesis inhibitor diazaborine; may be involved in degradation of aberrant mRNAs

ALG2 ALG2 YGL065C GDP-Man:Man(1)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase

ChrVII:381271 to 379760 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1512 381271..379760

Mannosyltransferase in the N-linked glycosylation pathway; catalyzes two consecutive steps in the N-linked glycosylation pathway; alg2 mutants exhibit temperature-sensitive growth and abnormal accumulation of the lipid-linked oligosaccharide Man2GlcNAc2-PP-Dol

ARG2 ARG2 YJL071W HRB574, acetyl-CoA:L-glutamate N-acetyltransferase

ChrX:306132 to 307856 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1725 306132..307856

Acetylglutamate synthase (glutamate N-acetyltransferase); mitochondrial enzyme that catalyzes the first step in the biosynthesis of the arginine precursor ornithine; forms a complex with Arg5,6p

ATG2 ATG2 YNL242W SPO72, AUT8, APG2

ChrXIV:191324 to 196102 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..4779 191324..196102

Peripheral membrane protein required for autophagic vesicle formation; also required for vesicle formation during pexophagy and the cytoplasm-to-vaucole targeting (Cvt) pathway; involved in Atg9p cycling between the phagophore assembly site and mitochondria; essential for cell cycle progression from G2/M to G1 under nitrogen starvation; forms cytoplasmic foci upon DNA replication stress

ATG20 ATG20 YDL113C SNX42, CVT20

ChrIV:258555 to 256633 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1923 258555..256633

Sorting nexin family member; required for the cytoplasm-to-vacuole targeting (Cvt) pathway and for endosomal sorting; has a Phox homology domain that binds phosphatidylinositol-3-phosphate; interacts with Snx4p; potential Cdc28p substrate

ATG21 ATG21 YPL100W MAI1, HSV1

ChrXVI:361872 to 363362 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1491 361872..363362

Phosphoinositide binding protein; required for vesicle formation in the cytoplasm-to-vacuole targeting (Cvt) pathway; binds both phosphatidylinositol (3,5)-bisphosphate and phosphatidylinositol 3-phosphate; WD-40 repeat protein

ATG22 ATG22 YCL038C AUT4

ChrIII:56527 to 54941 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1587 56527..54941

Vacuolar integral membrane protein required for efflux of amino acids; required for efflux of amino acids during autophagic body breakdown in the vacuole; null mutation causes a gradual loss of viability during starvation

ATG23 ATG23 YLR431C CVT23

ChrXII:1001703 to 1000342 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1362 1001703..1000342

Peripheral membrane protein required for autophagy and CVT; required for cytoplasm-to-vacuole targeting (Cvt) pathway and efficient macroautophagy; cycles between the phagophore assembly site (PAS) and non-PAS locations; forms a complex with Atg9p and Atg27p

ATG24 SNX4 YJL036W CVT13, ATG24

ChrX:378825 to 380096 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1272 378825..380096

Sorting nexin; involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans-Golgi network and in cytoplasm to vacuole transport; contains a PX phosphoinositide-binding domain; forms complexes with Snx41p and with Atg20p

ATG26 ATG26 YLR189C UGT51

ChrXII:534393 to 530797 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..3597 534393..530797

UDP-glucose:sterol glucosyltransferase; conserved enzyme involved in synthesis of sterol glucoside membrane lipids; in contrast to ATG26 from P. pastoris, S. cerevisiae ATG26 is not involved in autophagy

ATG27 ATG27 YJL178C ETF1

ChrX:90097 to 89282 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..816 90097..89282

Type I membrane protein involved in autophagy and the Cvt pathway; may be involved in membrane delivery to the phagophore assembly site

ATG29 ATG29 YPL166W

ChrXVI:237338 to 237979 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..642 237338..237979

Autophagy-specific protein; required for recruiting other ATG proteins to the pre-autophagosomal structure (PAS); interacts with Atg17p and localizas to the PAS in a manner interdependent with Atg17p and Cis1p; not conserved; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress

COG2 COG2 YGR120C SEC35

ChrVII:730821 to 730033 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..789 730821..730033

Essential component of the conserved oligomeric Golgi complex; a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments; the components of the Golgi complex are Gog1p through Cog8p

CSG2 CSG2 YBR036C CLS2, mannosylinositol phosphorylceramide synthase regulatory subunit

ChrII:310313 to 309081 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1233 310313..309081

Endoplasmic reticulum membrane protein; required for mannosylation of inositolphosphorylceramide and for growth at high calcium concentrations; protein abundance increases in response to DNA replication stress

DIG2 DIG2 YDR480W RST2

ChrIV:1417399 to 1418370 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..972 1417399..1418370

MAP kinase-responsive inhibitor of the Ste12p transcription factor; involved in the regulation of mating-specific genes and the invasive growth pathway; related regulators Dig1p and Dig2p bind to Ste12p; DIG2 has a paralog, DIG1, that arose from the whole genome duplication

DOG2 DOG2 YHR043C 2-deoxyglucose-6-phosphate phosphatase

ChrVIII:193545 to 192805 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..741 193545..192805

2-deoxyglucose-6-phosphate phosphatase; member of a family of low molecular weight phosphatases, induced by oxidative and osmotic stress, confers 2-deoxyglucose resistance when overexpressed; DOG2 has a paralog, DOG1, that arose from a single-locus duplication

DUG2 DUG2 YBR281C glutamine amidotransferase subunit DUG2

ChrII:767606 to 764970 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2637 767606..764970

Component of glutamine amidotransferase (GATase II); forms a complex with Dug3p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p)

eIF4G2 TIF4632 YGL049C eIF4G2

ChrVII:409604 to 406860 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2745 409604..406860

Translation initiation factor eIF4G; subunit of the mRNA cap-binding protein complex (eIF4F) that also contains eIF4E (Cdc33p); associates with the poly(A)-binding protein Pab1p, also interacts with eIF4A (Tif1p); TIF4632 has a paralog, TIF4631, that arose from the whole genome duplication

ENG2 ACF2 YLR144C ENG2, PCA1

ChrXII:432016 to 429677 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2340 432016..429677

Intracellular beta-1,3-endoglucanase; expression is induced during sporulation; may have a role in cortical actin cytoskeleton assembly; protein abundance increases in response to DNA replication stress

ERG2 ERG2 YMR202W END11, C-8 sterol isomerase ERG2

ChrXIII:667537 to 668205 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..669 667537..668205

C-8 sterol isomerase; catalyzes the isomerization of the delta-8 double bond to the delta-7 position at an intermediate step in ergosterol biosynthesis

ERG20 ERG20 YJL167W BOT3, FDS1, FPP1, bifunctional (2E,6E)-farnesyl diphosphate synthase/dimethylallyltranstransferase

ChrX:105014 to 106072 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1059 105014..106072

Farnesyl pyrophosphate synthetase; has both dimethylallyltranstransferase and geranyltranstransferase activities; catalyzes the formation of C15 farnesyl pyrophosphate units for isoprenoid and sterol biosynthesis

ERG24 ERG24 YNL280C delta(14)-sterol reductase

ChrXIV:110411 to 109095 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1317 110411..109095

C-14 sterol reductase; acts in ergosterol biosynthesis; mutants accumulate the abnormal sterol ignosterol (ergosta-8,14 dienol), and are viable under anaerobic growth conditions but inviable on rich medium under aerobic conditions

ERG25 ERG25 YGR060W methylsterol monooxygenase

ChrVII:610564 to 611493 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..930 610564..611493

C-4 methyl sterol oxidase; catalyzes the first of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; mutants accumulate the sterol intermediate 4,4-dimethylzymosterol

ERG26 ERG26 YGL001C sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating)

ChrVII:496502 to 495453 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1050 496502..495453

C-3 sterol dehydrogenase; catalyzes the second of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis

ERG27 ERG27 YLR100W 3-keto-steroid reductase

ChrXII:341810 to 342853 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1044 341810..342853

3-keto sterol reductase; catalyzes the last of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; mutants are sterol auxotrophs

ERG28 ERG28 YER044C BUD18

ChrV:238016 to 237570 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..447 238016..237570

Endoplasmic reticulum membrane protein; may facilitate protein-protein interactions between the Erg26p dehydrogenase and the Erg27p 3-ketoreductase and/or tether these enzymes to the ER, also interacts with Erg6p

ERG29 ERG29 YMR134W

ChrXIII:537838 to 538551 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..714 537838..538551

Protein of unknown function involved in ergosterol biosynthesis; conditional mutants produce less ergosterol, display impaired oxygen consumption, respiratory growth, mitochondrial iron utilization, and are more sensitive to oxidative stress; mutant bm-8 has a growth defect on iron-limited medium that is complemented by overexpression of Yfh1p; protein localizes to the cytoplasm, ER and nuclear envelope; highly conserved in ascomycetes

ERG201 ERG201 ERG201

EXG2 EXG2 YDR261C

ChrIV:979209 to 977521 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1689 979209..977521

Genetic position: 162 cM

Exo-1,3-beta-glucanase; involved in cell wall beta-glucan assembly; may be anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor

FIG2 FIG2 YCR089W

ChrIII:267434 to 272263 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..4830 267434..272263

Cell wall adhesin, expressed specifically during mating; may be involved in maintenance of cell wall integrity during mating; FIG2 has a paralog, AGA1, that arose from the whole genome duplication

GIG2 SSN3 YPL042C GIG2, NUT7, SRB10, UME5, RYE5, CDK8, SSX7, URR1

ChrXVI:474707 to 473040 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1668 474707..473040

Cyclin-dependent protein kinase; component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression

GLG2 GLG2 YJL137C glycogenin glucosyltransferase GLG2

ChrX:156127 to 154985 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1143 156127..154985

Glycogenin glucosyltransferase; self-glucosylating initiator of glycogen synthesis, also glucosylates n-dodecyl-beta-D-maltoside; similar to mammalian glycogenin; GLG2 has a paralog, GLG1, that arose from the whole genome duplication

HMG2 HMG2 YLR450W hydroxymethylglutaryl-CoA reductase (NADPH) HMG2

ChrXII:1032627 to 1035764 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..3138 1032627..1035764

Genetic position: 343 cM

HMG-CoA reductase; converts HMG-CoA to mevalonate, a rate-limiting step in sterol biosynthesis; one of two isozymes; overproduction induces assembly of peripheral ER membrane arrays and short nuclear-associated membrane stacks; forms foci at the nuclear periphery upon DNA replication stress; HMG2 has a paralog, HMG1, that arose from the whole genome duplication

HOG2 TPS2 YDR074W HOG2, PFK3, trehalose-phosphatase TPS2

ChrIV:593893 to 596583 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2691 593893..596583

Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex; involved in synthesis of the storage carbohydrate trehalose; expression is induced by stress conditions and repressed by the Ras-cAMP pathway; protein abundance increases in response to DNA replication stress

IMG2 IMG2 YCR071C mitochondrial 54S ribosomal protein IMG2

ChrIII:240543 to 240103 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..441 240543..240103

Mitochondrial ribosomal protein of the large subunit; conserved in metazoa, with similarity to human mitochondrial ribosomal protein MRPL49

LAG2 LAG2 YOL025W ECM36

ChrXV:274957 to 276939 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1983 274957..276939

Protein that negatively regulates the SCF E3-ubiquitin ligase; regulates by interacting with and preventing neddyation of the cullin subunit, Cdc53p; longevity determinant that is preferentially expressed in young cells; similar to mammalian Cand1

MAG2 MAG2 YLR427W

ChrXII:988428 to 990440 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2013 988428..990440

Cytoplasmic protein of unknown function; induced in response to mycotoxin patulin; ubiquitinated protein similar to the human ring finger motif protein RNF10; predicted to be involved in repair of alkylated DNA due to interaction with MAG1

MIG2 MIG2 YGL209W MLZ1

ChrVII:95858 to 97006 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1149 95858..97006

Zinc finger transcriptional repressor; cooperates with Mig1p in glucose-induced repression of many genes; under low glucose conditions Mig2p relocalizes to mitochondrion, where it interacts with Ups1p and antagonizes mitochondrial fission factor, Dnm1p, indicative of a role in mitochondrial fusion or regulating morphology; regulates filamentous growth along with Mig2p in response to glucose depletion; MIG2 has a paralog, MIG3, that arose from the whole genome duplication

MTG2 MTG2 YHR168W putative GTPase MTG2

ChrVIII:440377 to 441933 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1557 440377..441933

Putative GTPase; member of the Obg family; peripheral protein of the mitochondrial inner membrane that associates with the large ribosomal subunit; required for mitochondrial translation, possibly via a role in ribosome assembly

NOG2 NOG2 YNR053C NUG2, putative GTPase NOG2

ChrXIV:723112 to 721120 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..810 723112..722303
Intron 811..1342 722302..721771
CDS 1343..1993 721770..721120

Putative GTPase; associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation

NRG2 NRG2 YBR066C

ChrII:370699 to 370037 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..663 370699..370037

Transcriptional repressor; mediates glucose repression and negatively regulates filamentous growth; NRG2 has a paralog, NRG1, that arose from the whole genome duplication

NSG2 NSG2 YNL156C

ChrXIV:341968 to 341069 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..900 341968..341069

Protein involved in regulation of sterol biosynthesis; specifically stabilizes Hmg2p, one of two HMG-CoA isoenzymes that catalyze the rate-limiting step in sterol biosynthesis; homolog of mammalian INSIG proteins; NSG2 has a paralog, NSG1, that arose from the whole genome duplication

NTG2 NTG2 YOL043C SCR2, bifunctional N-glycosylase/AP lyase NTG2

ChrXV:249534 to 248392 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1143 249534..248392

DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase; involved in base excision repair, localizes to the nucleus; sumoylated; NTG2 has a paralog, NTG1, that arose from the whole genome duplication

ogg2 NTG1 YAL015C FUN33, SCR1, ogg2, bifunctional N-glycosylase/AP lyase NTG1

ChrI:128102 to 126903 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1200 128102..126903

DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase; involved in base excision repair; acts in both nucleus and mitochondrion; creates a double-strand break at mtDNA origins that stimulates replication in response to oxidative stress; required for maintaining mitochondrial genome integrity; NTG1 has a paralog, NTG2, that arose from the whole genome duplication

PIG2 PIG2 YIL045W

ChrIX:271161 to 272777 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1617 271161..272777

Putative type-1 protein phosphatase targeting subunit; tethers Glc7p type-1 protein phosphatase to Gsy2p glycogen synthase; PIG2 has a paralog, GIP2, that arose from the whole genome duplication

RBG2 RBG2 YGR173W GIR1

ChrVII:843854 to 844960 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1107 843854..844960

Protein with a role in translation; forms a complex with Gir2p; has similarity to mammalian developmentally regulated GTP-binding protein

REG2 REG2 YBR050C

ChrII:338199 to 337183 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1017 338199..337183

Regulatory subunit of the Glc7p type-1 protein phosphatase; involved with Reg1p, Glc7p, and Snf1p in regulation of glucose-repressible genes, also involved in glucose-induced proteolysis of maltose permease; REG2 has a paralog, REG1, that arose from the whole genome duplication

RIG2 TFB3 YDR460W RIG2, TFIIH/NER complex subunit TFB3

ChrIV:1383811 to 1384776 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..966 1383811..1384776

Subunit of TFIIH and nucleotide excision repair factor 3 complexes; involved in transcription initiation, required for nucleotide excision repair; ring finger protein similar to mammalian CAK and TFIIH subunit

ROG2 NAT5 YOR253W ARD2, ROG2, NAA50

ChrXV:804377 to 804907 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..531 804377..804907

Subunit of protein N-terminal acetyltransferase NatA; NatA is comprised of Nat1p, Ard1p, and Nat5p; N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing

RRG2 CCM1 YGR150C RRG2, DMR1

ChrVII:793053 to 790459 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2595 793053..790459

Mitochondrial 15S rRNA-binding protein; required for intron removal of COB and COX1 pre-mRNAs; has separable roles in stabilizing mitochondrial 15S rRNA and in maturation of the COB and COX1 mRNAs; contains pentatricopeptide repeat (PPR) motifs; mutant is respiratory deficient and has defective plasma membrane electron transport

RTG2 RTG2 YGL252C

ChrVII:27484 to 25718 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1767 27484..25718

Sensor of mitochondrial dysfunction; regulates the subcellular location of Rtg1p and Rtg3p, transcriptional activators of the retrograde (RTG) and TOR pathways; Rtg2p is inhibited by the phosphorylated form of Mks1p

SCG2 RAM1 YDL090C DPR1, FUS8, SCG2, SGP2, STE16, protein farnesyltransferase

ChrIV:296329 to 295034 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1296 296329..295034

Genetic position: -33 cM

Beta subunit of the CAAX farnesyltransferase (FTase); this complex prenylates the a-factor mating pheromone and Ras proteins; required for the membrane localization of Ras proteins and a-factor; homolog of the mammalian FTase beta subunit

SEG2 SEG2 YKL105C

ChrXI:242583 to 239185 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..3399 242583..239185

Eisosome component; likely plays only minor role in eisosome assembly; shown to interact with Seg1p; similar to A. gossypii SEG gene which is important for stabilizing eisosomes; SEG2 has a paralog, SEG1, that arose from the whole genome duplication

SOG2 SOG2 YOR353C

ChrXV:1000828 to 998453 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2376 1000828..998453

Key component of the RAM signaling network; required for proper cell morphogenesis and cell separation after mitosis

SUG2 RPT4 YOR259C CRL13, PCS1, SUG2, proteasome regulatory particle base subunit RPT4

ChrXV:813708 to 812395 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1314 813708..812395

Genetic position: 143 cM

ATPase of the 19S regulatory particle of the 26S proteasome; one of six ATPases of the regulatory particle; involved in degradation of ubiquitinated substrates; contributes preferentially to ERAD; required for spindle pole body duplication; mainly nuclear localization

tD(GUC)G2 tD(GUC)G2

ChrVII:544648 to 544577 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
Noncoding exon 1..72 544648..544577

Aspartate tRNA (tRNA-Asp), predicted by tRNAscan-SE analysis

tE(UUC)G2 tE(UUC)G2

ChrVII:401598 to 401527 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
Noncoding exon 1..72 401598..401527

Glutamate tRNA (tRNA-Glu), predicted by tRNAscan-SE analysis; thiolation of uridine at wobble position (34) requires Ncs6p

TFG2 TFG2 YGR005C transcription factor IIF subunit TFG2

ChrVII:505859 to 504657 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1203 505859..504657

TFIIF (Transcription Factor II) middle subunit; involved in both transcription initiation and elongation of RNA polymerase II; homologous to human RAP30

tG(GCC)G2 tG(GCC)G2

ChrVII:931023 to 930953 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
Noncoding exon 1..71 931023..930953

Glycine tRNA (tRNA-Gly), predicted by tRNAscan-SE analysis

tH(GUG)G2 tH(GUG)G2

ChrVII:319781 to 319852 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
Noncoding exon 1..72 319781..319852

Histidine tRNA (tRNA-His), predicted by tRNAscan-SE analysis

tK(CUU)G2 tK(CUU)G2

ChrVII:185786 to 185714 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
Noncoding exon 1..73 185786..185714

Lysine tRNA (tRNA-Lys), predicted by tRNAscan-SE analysis; a small portion is imported into mitochondria via interaction with mt lysyl-tRNA synthetase Msk1p and is necessary to decode AAG codons at high temperature, when base modification of mt-encoded tRNA-Lys is reduced

tK(UUU)G2 tK(UUU)G2

ChrVII:701048 to 700953 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
Noncoding exon 1..37 701048..701012
Intron 38..60 701011..700989
Noncoding exon 61..96 700988..700953

Lysine tRNA (tRNA-Lys), predicted by tRNAscan-SE analysis; thiolation of uridine at wobble position (34) requires Ncs6p

tL(CAA)G2 SUP54 tL(CAA)G2

ChrVII:423092 to 423205 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
Noncoding exon 1..38 423092..423129
Intron 39..70 423130..423161
Noncoding exon 71..114 423162..423205

Genetic position: -24 cM

Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE analysis; can mutate to suppress amber nonsense mutations

TLG2 TLG2 YOL018C

ChrXV:292074 to 290881 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1194 292074..290881

Syntaxin-like t-SNARE; forms a complex with Tlg1p and Vti1p and mediates fusion of endosome-derived vesicles with the late Golgi; binds Vps45p, which prevents Tlg2p degradation and also facilitates t-SNARE complex formation; homologous to mammalian SNARE protein syntaxin 16 (Sx16)

tR(UCU)G2 tR(UCU)G2

ChrVII:828794 to 828723 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
Noncoding exon 1..72 828794..828723

Arginine tRNA (tRNA-Arg), predicted by tRNAscan-SE analysis; one of 11 nuclear tRNA genes containing the tDNA-anticodon UCU (converted to mcm5-UCU in the mature tRNA), decodes AGA codons into arginine, one of 19 nuclear tRNAs for arginine

TSG2 TAF4 YMR005W TAF48, TSG2, MPT1, TafII48

ChrXIII:276045 to 277211 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1167 276045..277211

TFIID subunit (48 kDa); involved in RNA polymerase II transcription initiation; potential Cdc28p substrate

tT(UGU)G2 tT(UGU)G2

ChrVII:1004216 to 1004287 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
Noncoding exon 1..72 1004216..1004287

Threonine tRNA (tRNA-Thr), predicted by tRNAscan-SE analysis

tV(AAC)G2 tV(AAC)G2

ChrVII:823482 to 823555 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
Noncoding exon 1..74 823482..823555

Valine tRNA (tRNA-Val), predicted by tRNAscan-SE analysis

tW(CCA)G2 tW(CCA)G2

ChrVII:878815 to 878710 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
Noncoding exon 1..36 878815..878780
Intron 37..70 878779..878746
Noncoding exon 71..106 878745..878710

Tryptophan tRNA (tRNA-Trp), predicted by tRNAscan-SE analysis

YNG2 YNG2 YHR090C NBN1, EAF4

ChrVIII:284625 to 283777 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..849 284625..283777

Subunit of NuA4, an essential histone acetyltransferase complex; positions Piccolo NuA4 for efficient acetylation of histone H4 or histone H2A; relocalizes to the cytosol in response to hypoxia; similar to human tumor suppressor ING1 and its isoforms ING4 and ING5