Standard Name	FYV7
Systematic Name	YLR068W
Feature Type	ORF, Verified
Description	Essential protein required for maturation of 18S rRNA; required for survival upon exposure to K1 killer toxin (1, 2)
Name Description	Function required for Yeast Viability 1

Chromosomal Location	ChrXII:271008 to 271463 | ORF Map | GBrowse

	View Computational GO annotations for FYV7
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (IMP)
Cellular Component
High-throughput	nucleolus (IDA) nucleus (IDA)

Classical genetics
null	35S pre-rRNA accumulation: increased aberrant 23S rRNA processing intermediate accumulation: increased 27SA2 rRNA processing intermediate accumulation: decreased 20S rRNA processing intermediate accumulation: decreased metal resistance: decreased resistance to bortezomib: increased
Large-scale survey
null	cell cycle progression in G1 phase: increased duration cell size: decreased glycogen accumulation: increased competitive fitness: decreased dessication resistance: decreased fermentative growth: decreased rate haploproficient heat sensitivity: increased lifespan: increased resistance to cycloheximide: decreased resistance to arsenite(3-): decreased resistance to nickel sulfate: decreased resistance to caffeine: decreased resistance to sodium arsenite: increased stress resistance: increased vacuolar morphology: abnormal vegetative growth: decreased rate viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	16 total interaction(s) for 16 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 2
Genetic Interactions	Negative Genetic: 11 Positive Genetic: 1 Synthetic Growth Defect: 1 Synthetic Lethality: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXII:271008 to 271463 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..456 271008..271463 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004058