FOX2/YKR009C Summary

FOX2 BASIC INFORMATION

Standard Name	FOX2
Systematic Name	YKR009C
Alias	POX2
Feature Type	ORF, Verified
Description	Multifunctional enzyme of the peroxisomal fatty acid beta-oxidation pathway; has 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities (1)
Name Description	Fatty acid OXidation

GO Annotations	All FOX2 GO evidence and references
	View Computational GO annotations for FOX2
Molecular Function
Manually curated	3-hydroxyacyl-CoA dehydrogenase activity (IDA) enoyl-CoA hydratase activity (IDA)
Biological Process
Manually curated	fatty acid beta-oxidation (IMP)
Cellular Component
Manually curated	peroxisomal matrix (TAS)

Pathways	fatty acid oxidation pathway

Mutant Phenotype	All FOX2 Phenotype details and references
Large-scale survey
null	resistance to oleate: decreased resistance to nickel sulfate: decreased viable

Interactions	FOX2 All interactions details and references
	22 total interaction(s) for 22 unique genes/features.
Physical Interactions	Affinity Capture-MS: 5 Affinity Capture-RNA: 1 Affinity Capture-Western: 1 Biochemical Activity: 10 Co-fractionation: 1 Reconstituted Complex: 1 Two-hybrid: 1
Genetic Interactions	Phenotypic Enhancement: 2

Sequence Information

ChrXI:456697 to 453995 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2005-12-15 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..2703	456697..453995	2005-12-15	1996-07-31

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000001717

FOX2 RESOURCES

Click on map for expanded view

SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for FOX2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for FOX2]

1)	Hiltunen JK, et al. (2003) The biochemistry of peroxisomal beta-oxidation in the yeast Saccharomyces cerevisiae. FEMS Microbiol Rev 27(1):35-64

SGD^tm pages Database Copyright © 1997-2010 The Board of Trustees of Leland Stanford Junior University. Permission to use the information contained in this database was given by the researchers/institutes who contributed or published the information. Users of the database are solely responsible for compliance with any copyright restrictions, including those applying to the author abstracts. Documents from this server are provided "AS-IS" without any warranty, expressed or implied. The SGD project at Stanford University is supported by a Genome Research Resource Grant from the US National Human Genome Research Institute, part of the US National Institutes of Health.