FLC1/YPL221W Summary Help

Standard Name FLC1 1
Systematic Name YPL221W
Feature Type ORF, Verified
Description Putative FAD transporter; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance; FLC1 has a paralog, FLC3, that arose from the whole genome duplication (1, 2)
Name Description FLavin Carrier 1
Chromosomal Location
ChrXVI:133043 to 135424 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All FLC1 GO evidence and references
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 2 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
41 total interaction(s) for 38 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • PCA: 23

Genetic Interactions
  • Dosage Rescue: 10
  • Negative Genetic: 4
  • Positive Genetic: 1
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 793
Molecular Weight (Da) 89,290
Isoelectric Point (pI) 8
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:133043 to 135424 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2382 133043..135424 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Retired NameHUF1, BOP1
Primary SGDIDS000006142
References cited on this page View Complete Literature Guide for FLC1
1) Protchenko O, et al.  (2006) A screen for genes of heme uptake identifies the FLC family required for import of FAD into the endoplasmic reticulum. J Biol Chem 281(30):21445-57
2) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61