Standard Name	FIR1 1
Systematic Name	YER032W
Alias	PIP1
Feature Type	ORF, Verified
Description	Protein involved in 3' mRNA processing, interacts with Ref2p; potential Cdc28p substrate (2)
Name Description	Factor Interacting with REF2

Chromosomal Location	ChrV:215063 to 217693 | ORF Map | GBrowse

	View Computational GO annotations for FIR1
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	mRNA polyadenylation (IGI, IMP) RNA polyadenylation (IGI, IMP)
Cellular Component
High-throughput	cellular bud neck (IDA)

Large-scale survey
null	competitive fitness: increased haploproficient resistance to caffeine: decreased resistance to benzo[a]pyrene: decreased resistance to mycophenolic acid: increased resistance to camptothecin: decreased resistance to cycloheximide: increased resistance to methyl methanesulfonate: decreased starvation resistance: decreased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	71 total interaction(s) for 64 unique genes/features.
Physical Interactions	Affinity Capture-MS: 5 Affinity Capture-Western: 1 Biochemical Activity: 2 Reconstituted Complex: 1 Two-hybrid: 25
Genetic Interactions	Dosage Lethality: 1 Dosage Rescue: 1 Negative Genetic: 31 Phenotypic Enhancement: 1 Positive Genetic: 2 Synthetic Lethality: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrV:215063 to 217693 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 2003-09-22
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..2631 215063..217693 2011-02-03 2003-09-22
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000834