FAT3/YKL187C Summary Help

Standard Name FAT3 1
Systematic Name YKL187C
Feature Type ORF, Verified
Description Protein required for fatty acid uptake; protein abundance increases in cortical patches in response to oleate exposure; the authentic, non-tagged protein is detected in a phosphorylated state in highly purified mitochondria in high-throughput studies; FAT3 has a paralog, YLR413W, that arose from the whole genome duplication (1, 2, 3, 4, 5)
Name Description FATty acid transporter 3 1
Chromosomal Location
ChrXI:91536 to 89284 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gene Ontology Annotations All FAT3 GO evidence and references
  View Computational GO annotations for FAT3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Large-scale survey
11 total interaction(s) for 9 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2

Genetic Interactions
  • Dosage Lethality: 1
  • Negative Genetic: 4
  • Positive Genetic: 2
  • Synthetic Growth Defect: 2

Expression Summary
Length (a.a.) 750
Molecular Weight (Da) 81,032
Isoelectric Point (pI) 4.72
Phosphorylation PhosphoGRID | PhosphoPep Database
sequence information
ChrXI:91536 to 89284 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Most Recent Updates
Coordinates Sequence
CDS 1..2253 91536..89284 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001670
References cited on this page View Complete Literature Guide for FAT3
1) Jung S, et al.  (2013) Global Analysis of Condition-specific Subcellular Protein Distribution and Abundance. Mol Cell Proteomics 12(5):1421-35
2) Sickmann A, et al.  (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
4) Reinders J, et al.  (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54
5) Reinders J, et al.  (2007) Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics 6(11):1896-906