Standard Name	FAR3 1
Systematic Name	YMR052W
Feature Type	ORF, Verified
Description	Protein of unknown function; involved in recovery from cell cycle arrest in response to pheromone, in a Far1p-independent pathway; interacts with Far7p, Far8p, Far9p, Far10p, and Far11p; localizes to the endoplasmic reticulum; protein abundance increases in response to DNA replication stress (2, 3, 4)
Name Description	Factor ARrest 5

Chromosomal Location	ChrXIII:379586 to 380200 | ORF Map | GBrowse

	View Computational GO annotations for FAR3
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	re-entry into mitotic cell cycle after pheromone arrest (IGI, IMP)
Cellular Component
Manually curated	endoplasmic reticulum (IDA)
High-throughput	endoplasmic reticulum (IDA)

Classical genetics
null	pheromone sensitivity: abnormal pheromone-induced cell cycle arrest: decreased recovery from pheromone-induced cell cycle arrest: increased rate viable
Large-scale survey
null	anaerobic growth: decreased auxotrophy glycogen accumulation: decreased competitive fitness: decreased resistance to bleomycin: increased resistance to caffeine: increased resistance to fenpropimorph: increased resistance to fluconazole: decreased resistance to mycophenolic acid: decreased resistance to camptothecin: decreased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	217 total interaction(s) for 145 unique genes/features.
Physical Interactions	Affinity Capture-MS: 2 Affinity Capture-RNA: 1 Affinity Capture-Western: 3 Biochemical Activity: 1 PCA: 1 Two-hybrid: 26
Genetic Interactions	Dosage Lethality: 2 Negative Genetic: 151 Phenotypic Enhancement: 3 Positive Genetic: 20 Synthetic Growth Defect: 1 Synthetic Lethality: 4 Synthetic Rescue: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXIII:379586 to 380200 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..615 379586..380200 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004656