FAP1/YNL023C Summary Help

Standard Name FAP1 1
Systematic Name YNL023C
Feature Type ORF, Verified
Description Protein that binds to Fpr1p; confers rapamycin resistance by competing with rapamycin for Fpr1p binding; accumulates in the nucleus upon treatment of cells with rapamycin; has similarity to D. melanogaster shuttle craft and human NFX1 (1)
Name Description FKBP12-Associated Protein 1
Chromosomal Location
ChrXIV:591160 to 588263 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All FAP1 GO evidence and references
  View Computational GO annotations for FAP1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 3 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
Resources
45 total interaction(s) for 30 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 22
  • Co-localization: 1
  • Co-purification: 1
  • Protein-peptide: 1
  • Two-hybrid: 5

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 13
  • Positive Genetic: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 965
Molecular Weight (Da) 108,494
Isoelectric Point (pI) 7.73
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:591160 to 588263 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2898 591160..588263 2011-02-03 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004968
References cited on this page View Complete Literature Guide for FAP1
1) Kunz J, et al.  (2000) FAP1, a homologue of human transcription factor NF-X1, competes with rapamycin for binding to FKBP12 in yeast. Mol Microbiol 37(6):1480-93