FAL1/YDR021W Summary Help

Standard Name FAL1 1
Systematic Name YDR021W
Feature Type ORF, Verified
Description Nucleolar protein required for maturation of 18S rRNA; member of the eIF4A subfamily of DEAD-box ATP-dependent RNA helicases (1, 2)
Name Description eukaryotic translation initiation factor Four A Like 1
Chromosomal Location
ChrIV:486804 to 488003 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All FAL1 GO evidence and references
  View Computational GO annotations for FAL1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 1 genes
Resources
Classical genetics
dominant negative
null
Large-scale survey
null
reduction of function
Resources
30 total interaction(s) for 27 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Affinity Capture-Western: 1
  • Biochemical Activity: 1

Genetic Interactions
  • Negative Genetic: 17
  • Phenotypic Suppression: 1
  • Positive Genetic: 2
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 3
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 399
Molecular Weight (Da) 45,213
Isoelectric Point (pI) 9.68
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:486804 to 488003 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1200 486804..488003 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002428
References cited on this page View Complete Literature Guide for FAL1
1) Kressler D, et al.  (1997) Fal1p is an essential DEAD-box protein involved in 40S-ribosomal-subunit biogenesis in Saccharomyces cerevisiae. Mol Cell Biol 17(12):7283-94
2) Wiederkehr T, et al.  (1998) Synthetic lethal interactions with conditional poly(A) polymerase alleles identify LCP5, a gene involved in 18S rRNA maturation. RNA 4(11):1357-72