Standard Name	EXG1 1
Systematic Name	YLR300W
Alias	BGL1
Feature Type	ORF, Verified
Description	Major exo-1,3-beta-glucanase of the cell wall; involved in cell wall beta-glucan assembly; exists as three differentially glycosylated isoenzymes; EXG1 has a paralog, SPR1, that arose from the whole genome duplication (2, 3, 4)
Name Description	EXo-1,3-beta-Glucanase 1

Chromosomal Location	ChrXII:728955 to 730301 | ORF Map | GBrowse
	Genetic position: 206 cM

	View Computational GO annotations for EXG1
Molecular Function
Manually curated	glucan exo-1,3-beta-glucosidase activity (ISS)
Biological Process
Manually curated	cellular glucan metabolic process (IGI, IMP) fungal-type cell wall organization (ISS)
Cellular Component
Manually curated	extracellular region (IDA) fungal-type cell wall (IDA)

Classical genetics
null	(1->6)-beta-D-glucan accumulation: increased killer toxin resistance: decreased
overexpression	(1->6)-beta-D-glucan accumulation: decreased killer toxin resistance: increased
Large-scale survey
null	competitive fitness: increased resistance to neomycin: decreased resistance to pentachlorophenol: decreased resistance to cycloheximide: decreased resistance to benzo[a]pyrene: decreased vacuolar morphology: abnormal viable
overexpression	vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	73 total interaction(s) for 56 unique genes/features.
Physical Interactions	Affinity Capture-MS: 6 Affinity Capture-RNA: 3
Genetic Interactions	Dosage Rescue: 3 Negative Genetic: 58 Positive Genetic: 1 Synthetic Growth Defect: 1 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXII:728955 to 730301 | ORF Map | GBrowse
	Genetic position: 206 cM
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1347 728955..730301 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004291