ESF2/YNR054C Summary Help

Standard Name ESF2 1
Systematic Name YNR054C
Alias ABT1 2
Feature Type ORF, Verified
Description Essential nucleolar protein involved in pre-18S rRNA processing; binds to RNA and stimulates ATPase activity of Dbp8; involved in assembly of the small subunit (SSU) processome (1, 2, 3)
Name Description Eighteen S rRNA Factor 2 1
Chromosomal Location
ChrXIV:724306 to 723356 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All ESF2 GO evidence and references
  View Computational GO annotations for ESF2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 2 genes
Resources
Classical genetics
null
repressible
Large-scale survey
null
reduction of function
repressible
Resources
54 total interaction(s) for 43 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 47
  • Affinity Capture-Western: 1
  • PCA: 1
  • Reconstituted Complex: 1
  • Two-hybrid: 1

Genetic Interactions
  • Synthetic Lethality: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 316
Molecular Weight (Da) 36,408
Isoelectric Point (pI) 8.34
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:724306 to 723356 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..951 724306..723356 2011-02-03 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005337
References cited on this page View Complete Literature Guide for ESF2
1) Hoang T, et al.  (2005) Esf2p, a U3-associated factor required for small-subunit processome assembly and compaction. Mol Cell Biol 25(13):5523-34
2) Oda T, et al.  (2000) A novel TATA-binding protein-binding protein, ABT1, activates basal transcription and has a yeast homolog that is essential for growth. Mol Cell Biol 20(4):1407-18
3) Granneman S, et al.  (2006) The nucleolar protein Esf2 interacts directly with the DExD/H box RNA helicase, Dbp8, to stimulate ATP hydrolysis. Nucleic Acids Res 34(10):3189-99