Standard Name	ERV46
Systematic Name	YAL042W
Alias	FUN9 1
Feature Type	ORF, Verified
Description	Protein localized to COPII-coated vesicles, forms a complex with Erv41p; involved in the membrane fusion stage of transport (2)
Name Description	ER Vesicle

Chromosomal Location	ChrI:61316 to 62563 | ORF Map | GBrowse

	View Computational GO annotations for ERV46
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	ER to Golgi vesicle-mediated transport (IPI)
Cellular Component
Manually curated	ER to Golgi transport vesicle (IDA) integral to endoplasmic reticulum membrane (IDA) integral to Golgi membrane (IDA)

Classical genetics
null	metal resistance: decreased
Large-scale survey
null	polyphosphate accumulation: abnormal competitive fitness: decreased Fus-Mid-GFP distribution: abnormal resistance to hydroxyurea: increased resistance to caffeine: increased resistance to bleomycin: increased resistance to nickel(2+): decreased resistance to arsenite(3-): decreased resistance to camptothecin: decreased resistance to cycloheximide: decreased resistance to methyl methanesulfonate: increased resistance to trichothecene: increased vacuolar morphology: abnormal viable
overexpression	vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	102 total interaction(s) for 67 unique genes/features.
Physical Interactions	Affinity Capture-MS: 11 Affinity Capture-RNA: 3 Affinity Capture-Western: 3 Biochemical Activity: 2 Co-fractionation: 1 Co-purification: 1 PCA: 3 Two-hybrid: 1
Genetic Interactions	Negative Genetic: 57 Phenotypic Enhancement: 1 Positive Genetic: 12 Synthetic Growth Defect: 6 Synthetic Lethality: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrI:61316 to 62563 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1248 61316..62563 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000040