ERV14/YGL054C Summary Help

Standard Name ERV14 1
Systematic Name YGL054C
Feature Type ORF, Verified
Description COPII-coated vesicle protein; involved in vesicle formation and incorporation of specific secretory cargo; required for the delivery of bud-site selection protein Axl2p to cell surface; related to Drosophila cornichon; ERV14 has a paralog, ERV15, that arose from the whole genome duplication (1, 2, 3)
Name Description ER Vesicle 1
Chromosomal Location
ChrVII:401287 to 400871 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All ERV14 GO evidence and references
  View Computational GO annotations for ERV14
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 2 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
overexpression
Resources
489 total interaction(s) for 241 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 20
  • Affinity Capture-RNA: 4
  • Affinity Capture-Western: 2
  • Co-fractionation: 1
  • Co-localization: 1
  • Co-purification: 1
  • PCA: 3
  • Reconstituted Complex: 1
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Rescue: 3
  • Negative Genetic: 326
  • Phenotypic Enhancement: 9
  • Phenotypic Suppression: 61
  • Positive Genetic: 47
  • Synthetic Growth Defect: 4
  • Synthetic Lethality: 5

Resources
Expression Summary
histogram
Resources
Length (a.a.) 138
Molecular Weight (Da) 15,930
Isoelectric Point (pI) 6.93
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:401287 to 400871 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..417 401287..400871 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003022
References cited on this page View Complete Literature Guide for ERV14
1) Powers J and Barlowe C  (1998) Transport of axl2p depends on erv14p, an ER-vesicle protein related to the Drosophila cornichon gene product. J Cell Biol 142(5):1209-22
2) Otte S, et al.  (2001) Erv41p and Erv46p: new components of COPII vesicles involved in transport between the ER and Golgi complex. J Cell Biol 152(3):503-18
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61