ERV14/YGL054C Summary

ERV14 BASIC INFORMATION

Standard Name	ERV14
Systematic Name	YGL054C
Feature Type	ORF, Verified
Description	Protein localized to COPII-coated vesicles, involved in vesicle formation and incorporation of specific secretory cargo; required for the delivery of bud-site selection protein Axl2p to cell surface; related to Drosophila cornichon (1, 2)
Name Description	ER Vesicle

GO Annotations	All ERV14 GO evidence and references
	View Computational GO annotations for ERV14
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	ascospore formation (IMP) axial cellular bud site selection (IMP) ER to Golgi vesicle-mediated transport (IMP, IPI)
Cellular Component
Manually curated	endoplasmic reticulum membrane (IDA) ER to Golgi transport vesicle (IDA)

Mutant Phenotype	All ERV14 Phenotype details and references
Classical genetics
null	axial budding pattern: decreased resistance to FK506: decreased
Large-scale survey
null	glycogen accumulation: increased competitive fitness: decreased resistance to rapamycin: decreased resistance to wortmannin: increased resistance to ethanol: decreased sporulation: absent viable

Interactions	ERV14 All interactions details and references
	129 total interaction(s) for 70 unique genes/features.
Physical Interactions	Affinity Capture-Western: 1 Co-fractionation: 1 Co-localization: 1 Co-purification: 1 Reconstituted Complex: 1 Two-hybrid: 4
Genetic Interactions	Dosage Rescue: 3 Phenotypic Enhancement: 102 Phenotypic Suppression: 8 Synthetic Growth Defect: 3 Synthetic Lethality: 4

Sequence Information

ChrVII:401290 to 400874 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2004-07-20 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..417	401290..400874	2004-07-20	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000003022

ERV14 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for ERV14

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for ERV14]

1)	Powers J and Barlowe C (1998) Transport of axl2p depends on erv14p, an ER-vesicle protein related to the Drosophila cornichon gene product. J Cell Biol 142(5):1209-22
2)	Otte S, et al. (2001) Erv41p and Erv46p: new components of COPII vesicles involved in transport between the ER and Golgi complex. J Cell Biol 152(3):503-18

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