ERP6/YGL002W Summary Help

Standard Name ERP6 1
Systematic Name YGL002W
Feature Type ORF, Verified
Description Member of the p24 family involved in ER to Golgi transport; similar to Emp24p and Erv25p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; ERP6 has a paralog, ERP1, that arose from the whole genome duplication (1, 2, 3, 4)
Name Description Emp24p/Erv25p Related Protein 1
Chromosomal Location
ChrVII:494517 to 495167 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All ERP6 GO evidence and references
  View Computational GO annotations for ERP6
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 83 genes
Resources
Large-scale survey
null
overexpression
Resources
30 total interaction(s) for 22 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 11
  • Affinity Capture-RNA: 3
  • PCA: 3
  • Two-hybrid: 7

Genetic Interactions
  • Negative Genetic: 3
  • Phenotypic Enhancement: 1
  • Positive Genetic: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 216
Molecular Weight (Da) 25,275
Isoelectric Point (pI) 6.53
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:494517 to 495167 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..651 494517..495167 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002970
References cited on this page View Complete Literature Guide for ERP6
1) Marzioch M, et al.  (1999) Erp1p and Erp2p, partners for Emp24p and Erv25p in a yeast p24 complex. Mol Biol Cell 10(6):1923-38
2) Springer S, et al.  (2000) The p24 proteins are not essential for vesicular transport in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 97(8):4034-9
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
4) Reinders J, et al.  (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54