ERC1/YHR032W Summary Help

Standard Name ERC1 1
Systematic Name YHR032W
Feature Type ORF, Verified
Description Member of the multi-drug and toxin extrusion (MATE) family; the MATE family is part of the multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) exporter superfamily; overproduction confers ethionine resistance and accumulation of S-adenosylmethionine (1, 2, 3, 4, 5)
Name Description Ethionine Resistance Conferring 1
Chromosomal Location
ChrVIII:173344 to 175089 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All ERC1 GO evidence and references
  View Computational GO annotations for ERC1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 5 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
overexpression
Resources
11 total interaction(s) for 11 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 1
  • PCA: 1
  • Two-hybrid: 1

Genetic Interactions
  • Negative Genetic: 6

Resources
Expression Summary
histogram
Resources
Length (a.a.) 581
Molecular Weight (Da) 64,208
Isoelectric Point (pI) 6.08
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVIII:173344 to 175089 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1746 173344..175089 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB
Primary SGDIDS000001074
References cited on this page View Complete Literature Guide for ERC1
1) Shiomi N, et al.  (1991) Nucleotide Sequence and Characterization of a Gene Conferring Resistance to Ethionine in Yeast Saccharomyces cerevisiae J Ferment Bioeng 71():211-215
2) Budovskaya YV, et al.  (2005) An evolutionary proteomics approach identifies substrates of the cAMP-dependent protein kinase. Proc Natl Acad Sci U S A 102(39):13933-8
3) Lee S-W, et al.  (2010) Overexpression of ethionine resistance gene for maximized production of S-adenosylmethionine in Saccharomyces cerevisiae sake kyokai No. 6 Korean J. Chem. Eng. 27(2):587-589
4) Crouse G  (2010) The sequence of ERC1/YHR032W from strain S288C contains a potential sequence error or naturally occuring variation. ()
5) Hvorup RN, et al.  (2003) The multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) exporter superfamily. Eur J Biochem 270(5):799-813