ENT5/YDR153C Summary Help

Standard Name ENT5 1
Systematic Name YDR153C
Feature Type ORF, Verified
Description Protein containing an N-terminal epsin-like domain; involved in clathrin recruitment and traffic between the Golgi and endosomes; associates with the clathrin adaptor Gga2p, clathrin adaptor complex AP-1, and clathrin (1, 2)
Name Description Epsin N-Terminal homology 1
Chromosomal Location
ChrIV:767971 to 766736 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All ENT5 GO evidence and references
  View Computational GO annotations for ENT5
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 9 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
unspecified
Resources
140 total interaction(s) for 92 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 13
  • Affinity Capture-Western: 6
  • Biochemical Activity: 6
  • Reconstituted Complex: 3
  • Two-hybrid: 2

Genetic Interactions
  • Negative Genetic: 88
  • Phenotypic Enhancement: 2
  • Positive Genetic: 9
  • Synthetic Growth Defect: 4
  • Synthetic Haploinsufficiency: 1
  • Synthetic Lethality: 4
  • Synthetic Rescue: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 411
Molecular Weight (Da) 47,321
Isoelectric Point (pI) 6.44
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:767971 to 766736 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1236 767971..766736 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002560
References cited on this page View Complete Literature Guide for ENT5
1) Duncan MC, et al.  (2003) Yeast epsin-related proteins required for Golgi-endosome traffic define a gamma-adaptin ear-binding motif. Nat Cell Biol 5(1):77-81
2) Wendland B, et al.  (1999) Yeast epsins contain an essential N-terminal ENTH domain, bind clathrin and are required for endocytosis. EMBO J 18(16):4383-93