Standard Name	ENT5 1
Systematic Name	YDR153C
Feature Type	ORF, Verified
Description	Protein containing an N-terminal epsin-like domain involved in clathrin recruitment and traffic between the Golgi and endosomes; associates with the clathrin adaptor Gga2p, clathrin adaptor complex AP-1, and clathrin (1, 2)
Name Description	Epsin N-Terminal homology 1

Chromosomal Location	ChrIV:767971 to 766736 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for ENT5
Molecular Function
Manually curated	clathrin binding (IPI) phosphatidylinositol-3,5-bisphosphate binding (IDA, IMP)
Biological Process
Manually curated	early endosome to Golgi transport (IGI) Golgi to endosome transport (IMP) late endosome to vacuole transport via multivesicular body sorting pathway (IMP)
Cellular Component
Manually curated	clathrin vesicle coat (IDA) endosome (IDA)
High-throughput	cytoplasm (IDA)

Classical genetics
null	viable
Large-scale survey
null	competitive fitness: decreased haploinsufficient resistance to camptothecin: increased resistance to benzo[a]pyrene: decreased resistance to cycloheximide: increased resistance to bleomycin: decreased resistance to tunicamycin: increased resistance to fluconazole: increased resistance to fenpropimorph: increased starvation resistance: decreased viable
overexpression	vegetative growth: decreased vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	138 total interaction(s) for 91 unique genes/features.
Physical Interactions	Affinity Capture-MS: 12 Affinity Capture-Western: 6 Biochemical Activity: 6 Reconstituted Complex: 3 Two-hybrid: 2
Genetic Interactions	Negative Genetic: 87 Phenotypic Enhancement: 2 Positive Genetic: 9 Synthetic Growth Defect: 4 Synthetic Haploinsufficiency: 1 Synthetic Lethality: 4 Synthetic Rescue: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIV:767971 to 766736 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1236 767971..766736 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000002560