Standard Name	EMP24 1
Systematic Name	YGL200C
Alias	BST2 2
Feature Type	ORF, Verified
Description	Component of the p24 complex; binds to GPI anchor proteins and mediates their efficient transport from the ER to the Golgi; integral membrane protein that associates with endoplasmic reticulum-derived COPII-coated vesicles (2, 3, 4)
Name Description	EndoMembrane Protein 1

Chromosomal Location	ChrVII:123305 to 122694 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for EMP24
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	ER to Golgi vesicle-mediated transport (IMP, IPI) protein retention in ER lumen (IMP) vesicle organization (IGI, IMP)
Cellular Component
Manually curated	endoplasmic reticulum (IDA) ER to Golgi transport vesicle (IDA) integral to membrane (ISS)

Classical genetics
null	Gas1p-GFP accumulation: abnormal Gas1p modification: decreased viable
Large-scale survey
null	proton accumulation: increased chitin deposition: normal endocytosis: decreased protein transport: abnormal resistance to Calcofluor White: decreased resistance to PM02734: decreased resistance to methyl methanesulfonate: decreased resistance to dimethyl sulfoxide: decreased resistance to clioquinol: decreased resistance to (S)-lactic acid: increased vacuolar morphology: abnormal vegetative growth: decreased rate viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	205 total interaction(s) for 139 unique genes/features.
Physical Interactions	Affinity Capture-MS: 32 Affinity Capture-RNA: 3 Affinity Capture-Western: 11 Co-fractionation: 2 Co-purification: 2 PCA: 38 Protein-peptide: 2 Reconstituted Complex: 5
Genetic Interactions	Dosage Rescue: 1 Negative Genetic: 67 Phenotypic Enhancement: 4 Phenotypic Suppression: 2 Positive Genetic: 6 Synthetic Growth Defect: 16 Synthetic Haploinsufficiency: 1 Synthetic Lethality: 10 Synthetic Rescue: 3
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrVII:123305 to 122694 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..612 123305..122694 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000003168