EMP24/YGL200C Summary

EMP24 BASIC INFORMATION

Standard Name	EMP24 1
Systematic Name	YGL200C
Alias	BST2 2
Feature Type	ORF, Verified
Description	Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport (2, 3)

GO Annotations	All EMP24 GO evidence and references
	View Computational GO annotations for EMP24
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	ER to Golgi vesicle-mediated transport (IMP, IPI) protein retention in ER lumen (IMP) vesicle organization (IGI, IMP)
Cellular Component
Manually curated	endoplasmic reticulum (IDA) ER to Golgi transport vesicle (IDA) integral to membrane (ISS)

Mutant Phenotype	All EMP24 Phenotype details and references
Large-scale survey
null	chitin deposition: normal resistance to Calcofluor White: decreased resistance to PM02734: decreased viable

Interactions	EMP24 All interactions details and references
	144 total interaction(s) for 96 unique genes/features.
Physical Interactions	Affinity Capture-MS: 24 Affinity Capture-RNA: 1 Affinity Capture-Western: 5 Co-fractionation: 2 Co-purification: 2 Reconstituted Complex: 5 Two-hybrid: 38
Genetic Interactions	Dosage Rescue: 1 Phenotypic Enhancement: 38 Phenotypic Suppression: 4 Synthetic Growth Defect: 8 Synthetic Haploinsufficiency: 1 Synthetic Lethality: 14 Synthetic Rescue: 1

Sequence Information

ChrVII:123310 to 122699 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2004-07-20 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..612	123310..122699	2004-07-20	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000003168

EMP24 RESOURCES

Click on map for expanded view

SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for EMP24

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for EMP24]

1)	Schimmoller F, et al. (1995) The absence of Emp24p, a component of ER-derived COPII-coated vesicles, causes a defect in transport of selected proteins to the Golgi. EMBO J 14(7):1329-39
2)	Elrod-Erickson MJ and Kaiser CA (1996) Genes that control the fidelity of endoplasmic reticulum to Golgi transport identified as suppressors of vesicle budding mutations. Mol Biol Cell 7(7):1043-58
3)	Otte S, et al. (2001) Erv41p and Erv46p: new components of COPII vesicles involved in transport between the ER and Golgi complex. J Cell Biol 152(3):503-18

SGD^tm pages Database Copyright © 1997-2010 The Board of Trustees of Leland Stanford Junior University. Permission to use the information contained in this database was given by the researchers/institutes who contributed or published the information. Users of the database are solely responsible for compliance with any copyright restrictions, including those applying to the author abstracts. Documents from this server are provided "AS-IS" without any warranty, expressed or implied. The SGD project at Stanford University is supported by a Genome Research Resource Grant from the US National Human Genome Research Institute, part of the US National Institutes of Health.