EGT2/YNL327W Summary Help

Standard Name EGT2
Systematic Name YNL327W
Feature Type ORF, Verified
Description Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase; required for proper cell separation after cytokinesis; expression is activated by Swi5p and tightly regulated in a cell cycle-dependent manner (1, 2, 3)
Name Description
Chromosomal Location
ChrXIV:24048 to 27173 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All EGT2 GO evidence and references
  View Computational GO annotations for EGT2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 19 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
19 total interaction(s) for 16 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 6
  • Protein-RNA: 1
  • Two-hybrid: 1

Genetic Interactions
  • Negative Genetic: 5
  • Positive Genetic: 3
  • Synthetic Rescue: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,041
Molecular Weight (Da) 108,525
Isoelectric Point (pI) 4.43
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:24048 to 27173 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2011-02-03
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..3126 24048..27173 2011-02-03 2011-02-03
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005271
References cited on this page View Complete Literature Guide for EGT2
1) Kovacech B, et al.  (1996) EGT2 gene transcription is induced predominantly by Swi5 in early G1. Mol Cell Biol 16(7):3264-74
2) Pan X and Heitman J  (2000) Sok2 regulates yeast pseudohyphal differentiation via a transcription factor cascade that regulates cell-cell adhesion. Mol Cell Biol 20(22):8364-72
3) Terashima H, et al.  (2003) The localization change of Ybr078w/Ecm33, a yeast GPI-associated protein, from the plasma membrane to the cell wall, affecting the cellular function. FEMS Microbiol Lett 218(1):175-80