EGD2/YHR193C Summary Help

Standard Name EGD2 1
Systematic Name YHR193C
Feature Type ORF, Verified
Description Alpha subunit of the nascent polypeptide-associated complex (NAC); involved in protein sorting and translocation; associated with cytoplasmic ribosomes (1, 2, 3)
Name Description Enhancer of Gal4 DNA binding 1
Chromosomal Location
ChrVIII:488236 to 487712 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All EGD2 GO evidence and references
  View Computational GO annotations for EGD2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 144 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
97 total interaction(s) for 78 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 29
  • Affinity Capture-RNA: 4
  • Affinity Capture-Western: 13
  • Biochemical Activity: 1
  • Co-fractionation: 2
  • Co-purification: 1
  • PCA: 6
  • Two-hybrid: 7

Genetic Interactions
  • Negative Genetic: 23
  • Phenotypic Enhancement: 1
  • Phenotypic Suppression: 1
  • Positive Genetic: 4
  • Synthetic Growth Defect: 4
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 174
Molecular Weight (Da) 18,709
Isoelectric Point (pI) 4.67
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVIII:488236 to 487712 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2005-11-07 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..525 488236..487712 2005-11-07 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001236
References cited on this page View Complete Literature Guide for EGD2
1) Shi X, et al.  (1995) The yeast EGD2 gene encodes a homologue of the alpha NAC subunit of the human nascent-polypeptide-associated complex. Gene 165(2):199-202
2) George R, et al.  (1998) The yeast nascent polypeptide-associated complex initiates protein targeting to mitochondria in vivo. Proc Natl Acad Sci U S A 95(5):2296-301
3) Reimann B, et al.  (1999) Initial characterization of the nascent polypeptide-associated complex in yeast. Yeast 15(5):397-407