Standard Name	EFB1
Systematic Name	YAL003W
Alias	TEF5
Feature Type	ORF, Verified
Description	Translation elongation factor 1 beta; stimulates nucleotide exchange to regenerate EF-1 alpha-GTP for the next elongation cycle; part of the EF-1 complex, which facilitates binding of aminoacyl-tRNA to the ribosomal A site (1)
Name Description	Elongation Factor Beta 2
Gene Product Alias	EF-1beta 2 , eEF1Balpha 3

Chromosomal Location	ChrI:142174 to 143160 | ORF Map | GBrowse

	View Computational GO annotations for EFB1
Molecular Function
Manually curated	guanyl-nucleotide exchange factor activity (IDA)
Biological Process
Manually curated	translational elongation (TAS)
Cellular Component
Manually curated	eukaryotic translation elongation factor 1 complex (IMP)

Classical genetics
dominant negative	heat sensitivity: increased
null	inviable
reduction of function	heat sensitivity: increased resistance to hygromycin B: decreased
unspecified	actin cytoskeleton morphology: abnormal cell size: increased
Large-scale survey
null	filamentous growth: increased haploinsufficient invasive growth: absent inviable starvation resistance: decreased
reduction of function	competitive fitness: decreased
Resources	PROPHECY | PhenoM | SCMD | ScreenTroll | Yeast Fitness Database

	69 total interaction(s) for 52 unique genes/features.
Physical Interactions	Affinity Capture-MS: 18 Affinity Capture-RNA: 6 Affinity Capture-Western: 3 Co-crystal Structure: 4 Two-hybrid: 2
Genetic Interactions	Dosage Rescue: 3 Negative Genetic: 25 Positive Genetic: 3 Synthetic Lethality: 5
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Mass Spec

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrI:142174 to 143160 | ORF Map | GBrowse
	This feature contains embedded feature(s): SNR18
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..80 142174..142253 2011-02-03 1999-07-17 Intron 81..446 142254..142619 2011-02-03 1999-07-17 CDS 447..987 142620..143160 2011-02-03 1999-07-17
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS) Intron (81 - 446)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000003