ECM5/YMR176W Summary Help

Standard Name ECM5 1
Systematic Name YMR176W
Feature Type ORF, Verified
Description Non-essential protein of unknown function; contains ATP/GTP-binding site motif A; null mutant exhibits cellular volume up to four times greater than wild-type, also large drooping buds with elongated necks; relative distribution to the nucleus increases upon DNA replication stress (1, 2)
Name Description ExtraCellular Mutant 1
Chromosomal Location
ChrXIII:611740 to 615975 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All ECM5 GO evidence and references
  View Computational GO annotations for ECM5
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Classical genetics
null
unspecified
Large-scale survey
null
unspecified
Resources
31 total interaction(s) for 26 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 11
  • Affinity Capture-Western: 2
  • Two-hybrid: 2

Genetic Interactions
  • Negative Genetic: 13
  • Phenotypic Enhancement: 1
  • Phenotypic Suppression: 1
  • Positive Genetic: 1

Resources
Expression Summary
histogram
Resources
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:611740 to 615975 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..4236 611740..615975 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004788
References cited on this page View Complete Literature Guide for ECM5
1) Lussier M, et al.  (1997) Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae. Genetics 147(2):435-50
2) Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76