ECM32/YER176W Summary Help

Standard Name ECM32 1
Systematic Name YER176W
Alias HEL1 , MTT1
Feature Type ORF, Verified
Description DNA dependent ATPase/DNA helicase; helicase belonging to the Dna2p- and Nam7p-like family of helicases that is involved in modulating translation termination; interacts with the translation termination factors, localized to polysomes (2, 3, 4)
Name Description ExtraCellular Mutant
Chromosomal Location
ChrV:541690 to 545055 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All ECM32 GO evidence and references
  View Computational GO annotations for ECM32
Molecular Function
Manually curated
High-throughput
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 2 genes
Resources
Classical genetics
unspecified
Large-scale survey
null
overexpression
unspecified
Resources
15 total interaction(s) for 15 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3

Genetic Interactions
  • Dosage Lethality: 1
  • Negative Genetic: 8
  • Phenotypic Suppression: 1
  • Positive Genetic: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,121
Molecular Weight (Da) 126,969
Isoelectric Point (pI) 10.17
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrV:541690 to 545055 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..3366 541690..545055 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000978
References cited on this page View Complete Literature Guide for ECM32
1) Lussier M, et al.  (1997) Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae. Genetics 147(2):435-50
2) Bean DW and Matson SW  (1997) Identification of the gene encoding scHelI, a DNA helicase from Saccharomyces cerevisiae. Yeast 13(15):1465-75
3) Biswas EE, et al.  (1995) Biochemical and genetic characterization of a replication protein A dependent DNA helicase from the yeast, Saccharomyces cerevisiae. Biochem Biophys Res Commun 206(3):850-6
4) Czaplinski K, et al.  (2000) Mtt1 is a Upf1-like helicase that interacts with the translation termination factors and whose overexpression can modulate termination efficiency. RNA 6(5):730-43