ECM3/YOR092W Summary Help

Standard Name ECM3 1
Systematic Name YOR092W
Alias YOR3165W
Feature Type ORF, Verified
Description Non-essential protein of unknown function; involved in signal transduction and the genotoxic response; induced rapidly in response to treatment with 8-methoxypsoralen and UVA irradiation; relocalizes from ER to cytoplasm upon DNA replication stress; ECM3 has a paralog, YNL095C, that arose from the whole genome duplication (2, 3, 4)
Name Description ExtraCellular Mutant 1
Chromosomal Location
ChrXV:495127 to 496968 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All ECM3 GO evidence and references
  View Computational GO annotations for ECM3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Large-scale survey
null
overexpression
unspecified
Resources
29 total interaction(s) for 25 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Affinity Capture-RNA: 3
  • Biochemical Activity: 5
  • PCA: 4

Genetic Interactions
  • Negative Genetic: 11
  • Synthetic Growth Defect: 2
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 613
Molecular Weight (Da) 68,014
Isoelectric Point (pI) 8.16
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:495127 to 496968 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1842 495127..496968 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005618
References cited on this page View Complete Literature Guide for ECM3
1) Lussier M, et al.  (1997) Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae. Genetics 147(2):435-50
2) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
3) Dardalhon M, et al.  (2007) Specific transcriptional responses induced by 8-methoxypsoralen and UVA in yeast. FEMS Yeast Res 7(6):866-878
4) Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76