Standard Name	ECM29 1
Systematic Name	YHL030W
Feature Type	ORF, Verified
Description	Scaffold protein; assists in association of the proteasome core particle with the regulatory particle; degraded by the mature proteasome after assembly; contains HEAT-like repeats; protein increases in abundance and relocalizes from nucleus to cytoplasm upon DNA replication stress (2, 3, 4)
Name Description	ExtraCellular Mutant 1

Chromosomal Location	ChrVIII:40084 to 45690 | ORF Map | GBrowse

	View Computational GO annotations for ECM29
Molecular Function
Manually curated	protein complex scaffold (IDA)
Biological Process
Manually curated	proteasome assembly (IDA)
Cellular Component
Manually curated	nucleus (IDA) proteasome complex (IDA)
High-throughput	cytoplasm (IDA) nucleus (IDA)

Classical genetics
null	resistance to Calcofluor White: decreased
unspecified	resistance to hygromycin B: increased resistance to enzymatic treatment: decreased
Large-scale survey
null	competitive fitness: increased resistance to clioquinol: decreased resistance to cycloheximide: decreased resistance to sorbate: increased resistance to paromomycin: decreased transposable element transposition: increased utilization of nitrogen source: absent viable
unspecified	resistance to Calcofluor White: decreased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	280 total interaction(s) for 187 unique genes/features.
Physical Interactions	Affinity Capture-MS: 222 Affinity Capture-RNA: 1 Affinity Capture-Western: 13 Biochemical Activity: 1 Co-purification: 2 Two-hybrid: 1
Genetic Interactions	Negative Genetic: 15 Phenotypic Suppression: 6 Positive Genetic: 2 Synthetic Growth Defect: 3 Synthetic Lethality: 4 Synthetic Rescue: 10
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrVIII:40084 to 45690 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..5607 40084..45690 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001022