EAF7/YNL136W Summary Help

Standard Name EAF7 1
Systematic Name YNL136W
Feature Type ORF, Verified
Description Subunit of the NuA4 histone acetyltransferase complex; NuA4 acetylates the N-terminal tails of histones H4 and H2A (2)
Name Description Esa1-Associated Factor 1
Chromosomal Location
ChrXIV:370368 to 371645 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All EAF7 GO evidence and references
  View Computational GO annotations for EAF7
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 4 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
580 total interaction(s) for 351 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 53
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 7
  • Biochemical Activity: 8
  • Co-crystal Structure: 1

Genetic Interactions
  • Dosage Growth Defect: 32
  • Dosage Lethality: 5
  • Negative Genetic: 320
  • Positive Genetic: 22
  • Synthetic Growth Defect: 100
  • Synthetic Lethality: 25
  • Synthetic Rescue: 5

Resources
Expression Summary
histogram
Resources
Length (a.a.) 425
Molecular Weight (Da) 49,391
Isoelectric Point (pI) 4.99
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:370368 to 371645 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1278 370368..371645 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005080
References cited on this page View Complete Literature Guide for EAF7
1) Lacoste, N. and Cote, J.  (2003) Structure of the NuA4 histone acetyltransferase complex
2) Krogan NJ, et al.  (2004) Regulation of chromosome stability by the histone H2A variant Htz1, the Swr1 chromatin remodeling complex, and the histone acetyltransferase NuA4. Proc Natl Acad Sci U S A 101(37):13513-8