Standard Name	DYN2 1 (see Nomenclature conflict Note)
Systematic Name	YDR424C
Alias	SLC1 2
Feature Type	ORF, Verified
Description	Cytoplasmic light chain dynein, microtubule motor protein; proposed to be involved in the assembly of the nuclear pore complex (2, 3, 4)
Name Description	DYNein

Chromosomal Location	ChrIV:1319841 to 1319387 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for DYN2
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	actin filament-based process (IGI) microtubule-based process (IGI) nuclear pore complex assembly (IGI, IMP, IPI)
Cellular Component
Manually curated	cytoplasmic dynein complex (ISS) cytoplasmic microtubule (TAS) colocalizes_with nuclear pore (IDA) peroxisome (IDA)

Classical genetics
null	viable
Large-scale survey
null	anaerobic growth: decreased competitive fitness: decreased endocytosis: decreased resistance to cycloheximide: increased resistance to bleomycin: increased resistance to camptothecin: decreased resistance to caffeine: decreased resistance to mycophenolic acid: decreased resistance to methyl methanesulfonate: increased stress resistance: decreased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	124 total interaction(s) for 66 unique genes/features.
Physical Interactions	Affinity Capture-MS: 12 Affinity Capture-RNA: 1 Affinity Capture-Western: 2 Co-crystal Structure: 2 PCA: 1 Protein-peptide: 1 Reconstituted Complex: 5 Two-hybrid: 1
Genetic Interactions	Negative Genetic: 38 Phenotypic Enhancement: 4 Positive Genetic: 7 Synthetic Growth Defect: 26 Synthetic Lethality: 23 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIV:1319841 to 1319387 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..25 1319841..1319817 2011-02-03 1996-07-31 Intron 26..121 1319816..1319721 2011-02-03 1996-07-31 CDS 122..144 1319720..1319698 2011-02-03 1996-07-31 Intron 145..224 1319697..1319618 2011-02-03 1996-07-31 CDS 225..455 1319617..1319387 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS) Intron (26 - 121) Intron (145 - 224)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000002832