DUS4/YLR405W Summary Help

Standard Name DUS4 1
Systematic Name YLR405W
Feature Type ORF, Verified
Description Dihydrouridine synthase; member of a widespread family of conserved proteins including Smm1p, Dus1p, and Dus3p (2)
Name Description DihydroUridine Synthase 1, 2
Chromosomal Location
ChrXII:929789 to 930892 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All DUS4 GO evidence and references
  View Computational GO annotations for DUS4
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 5 genes
Resources
Large-scale survey
null
overexpression
Resources
9 total interaction(s) for 9 unique genes/features.
Physical Interactions
  • Co-purification: 1
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Lethality: 1
  • Negative Genetic: 2
  • Positive Genetic: 1
  • Synthetic Growth Defect: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 367
Molecular Weight (Da) 41,696
Isoelectric Point (pI) 7.8
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:929789 to 930892 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1104 929789..930892 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004397
References cited on this page View Complete Literature Guide for DUS4
1) Xing F, et al.  (2004) The specificities of four yeast dihydrouridine synthases for cytoplasmic tRNAs. J Biol Chem 279(17):17850-60
2) Xing F, et al.  (2002) A conserved family of Saccharomyces cerevisiae synthases effects dihydrouridine modification of tRNA. RNA 8(3):370-81