DUS1/YML080W Summary Help

Standard Name DUS1 1
Systematic Name YML080W
Feature Type ORF, Verified
Description Dihydrouridine synthase; member of a widespread family of conserved proteins including Smm1p, Dus3p, and Dus4p; modifies pre-tRNA(Phe) at U17 (1)
Name Description DihydroUridine Synthase 1
Chromosomal Location
ChrXIII:108806 to 110077 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All DUS1 GO evidence and references
  View Computational GO annotations for DUS1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 3 genes
Resources
Large-scale survey
null
overexpression
repressible
Resources
19 total interaction(s) for 19 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 1
  • Biochemical Activity: 5
  • Protein-peptide: 3

Genetic Interactions
  • Negative Genetic: 3
  • Positive Genetic: 2
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 423
Molecular Weight (Da) 48,131
Isoelectric Point (pI) 9.15
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:108806 to 110077 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1272 108806..110077 1996-07-31 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004545
References cited on this page View Complete Literature Guide for DUS1
1) Xing F, et al.  (2002) A conserved family of Saccharomyces cerevisiae synthases effects dihydrouridine modification of tRNA. RNA 8(3):370-81