DNM1/YLL001W Summary Help

DNM1 BASIC INFORMATION

Standard Name DNM1
Systematic Name YLL001W
Feature Type ORF, Verified
Description Dynamin-related GTPase required for mitochondrial fission and morphology; assembles on the cytoplasmic face of mitochondrial tubules at sites at which division will occur; also participates in endocytosis and regulating peroxisome abundance (1, 2, 3, 4, 5)
Name Description DyNaMin-related 6
GO Annotations All DNM1 GO evidence and references
    View Computational GO annotations for DNM1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Mutant Phenotype All DNM1 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions DNM1 All interactions details and references
67 total interaction(s) for 35 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 6
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 6
  • Biochemical Activity: 1
  • Co-fractionation: 1
  • Co-localization: 3
  • Co-purification: 1
  • PCA: 5
  • Reconstituted Complex: 2
  • Two-hybrid: 18
Genetic Interactions
  • Dosage Rescue: 1
  • Phenotypic Enhancement: 5
  • Phenotypic Suppression: 5
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 5
  • Synthetic Rescue: 5
Sequence Information
ChrXII:147889 to 150162 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..2274 147889..150162 1996-07-31 1996-07-31
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000003924

DNM1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Localization Resources
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  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for DNM1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for DNM1]

1) Otsuga D, et al.  (1998) The dynamin-related GTPase, Dnm1p, controls mitochondrial morphology in yeast. J Cell Biol 143(2):333-49
2) Gammie AE, et al.  (1995) DNM1, a dynamin-related gene, participates in endosomal trafficking in yeast. J Cell Biol 130(3):553-66
3) Bleazard W, et al.  (1999) The dynamin-related GTPase Dnm1 regulates mitochondrial fission in yeast. Nat Cell Biol 1(5):298-304
4) Mozdy AD, et al.  (2000) Dnm1p GTPase-mediated mitochondrial fission is a multi-step process requiring the novel integral membrane component Fis1p. J Cell Biol 151(2):367-80
5) Kuravi K, et al.  (2006) Dynamin-related proteins Vps1p and Dnm1p control peroxisome abundance in Saccharomyces cerevisiae. J Cell Sci 119(Pt 19):3994-4001
6) Gammie AE and Rose MD  (1995) Identification and characterization of CEN12 in the budding yeast Saccharomyces cerevisiae. Curr Genet 28(6):512-6