Standard Name	DNM1
Systematic Name	YLL001W
Feature Type	ORF, Verified
Description	Dynamin-related GTPase required for mitochondrial fission and morphology; assembles on the cytoplasmic face of mitochondrial tubules at sites at which division will occur; also participates in endocytosis and regulating peroxisome abundance (1, 2, 3, 4, 5)
Name Description	DyNaMin-related 6

Chromosomal Location	ChrXII:147890 to 150163 | ORF Map | GBrowse

	View Computational GO annotations for DNM1
Molecular Function
Manually curated	GTPase activity (IDA) identical protein binding (IDA) protein homodimerization activity (IDA)
Biological Process
Manually curated	chronological cell aging (IMP) mitochondrial fission (IGI, IMP) mitochondrion inheritance (IGI) mitochondrion localization (IGI) mitochondrion organization (IMP) peroxisome fission (IGI) peroxisome organization (IGI, IMP) protein homooligomerization (IDA)
Cellular Component
Manually curated	mitochondrial outer membrane (IDA) peroxisome (IDA)
High-throughput	mitochondrion (IDA)

Classical genetics
null	apoptosis: decreased tellurium atom accumulation: decreased lifespan: increased mitochondrial morphology: abnormal mitophagy: decreased peroxisomal morphology: abnormal resistance to BAR0329: increased resistance to hydrogen peroxide: increased survival rate in stationary phase: increased viability: decreased viable
Large-scale survey
null	competitive fitness: decreased dessication resistance: decreased mitochondrial morphology: abnormal mitophagy: absent viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	208 total interaction(s) for 100 unique genes/features.
Physical Interactions	Affinity Capture-MS: 15 Affinity Capture-RNA: 1 Affinity Capture-Western: 8 Co-fractionation: 1 Co-localization: 3 Co-purification: 1 PCA: 6 Reconstituted Complex: 3 Two-hybrid: 19
Genetic Interactions	Dosage Rescue: 1 Negative Genetic: 103 Phenotypic Enhancement: 11 Phenotypic Suppression: 12 Positive Genetic: 11 Synthetic Growth Defect: 7 Synthetic Rescue: 6
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXII:147890 to 150163 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..2274 147890..150163 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000003924