DGA1/YOR245C Summary Help

Standard Name DGA1 1
Systematic Name YOR245C
Feature Type ORF, Verified
Description Diacylglycerol acyltransferase; catalyzes the terminal step of triacylglycerol (TAG) formation, acylates diacylglycerol using acyl-CoA as an acyl donor; Lro1p and Dga1p can O-acylate ceramides; localized to lipid particles (2, 3)
Name Description DiacylGlycerol Acyltransferase 1
Chromosomal Location
ChrXV:795332 to 794076 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All DGA1 GO evidence and references
  View Computational GO annotations for DGA1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 2 genes
Resources
Pathways
Classical genetics
null
overexpression
Large-scale survey
null
overexpression
Resources
84 total interaction(s) for 38 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 1
  • Biochemical Activity: 1

Genetic Interactions
  • Dosage Growth Defect: 1
  • Negative Genetic: 37
  • Phenotypic Enhancement: 29
  • Phenotypic Suppression: 1
  • Positive Genetic: 3
  • Synthetic Growth Defect: 3
  • Synthetic Lethality: 5

Resources
Expression Summary
histogram
Resources
Length (a.a.) 418
Molecular Weight (Da) 47,711
Isoelectric Point (pI) 10.39
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:795332 to 794076 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1257 795332..794076 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005771
References cited on this page View Complete Literature Guide for DGA1
1) Oelkers P, et al.  (2002) The DGA1 gene determines a second triglyceride synthetic pathway in yeast. J Biol Chem 277(11):8877-81
2) Sorger D and Daum G  (2002) Synthesis of triacylglycerols by the acyl-coenzyme A:diacyl-glycerol acyltransferase Dga1p in lipid particles of the yeast Saccharomyces cerevisiae. J Bacteriol 184(2):519-24
3) Voynova NS, et al.  (2012) A novel pathway of ceramide metabolism in Saccharomyces cerevisiae. Biochem J 447(1):103-14