DCC1/YCL016C Summary Help

Standard Name DCC1 1
Systematic Name YCL016C
Feature Type ORF, Verified
Description Subunit of a complex with Ctf8p and Ctf18p; shares some components with Replication Factor C; required for sister chromatid cohesion and telomere length maintenance (1, 2)
Name Description Defective in sister Chromatid Cohesion 1
Chromosomal Location
ChrIII:95763 to 94621 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All DCC1 GO evidence and references
  View Computational GO annotations for DCC1
Molecular Function
Manually curated
Biological Process
Manually curated
High-throughput
Cellular Component
Manually curated
Regulators 2 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
630 total interaction(s) for 314 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 5
  • Affinity Capture-Western: 1
  • PCA: 1
  • Reconstituted Complex: 1

Genetic Interactions
  • Dosage Growth Defect: 1
  • Dosage Lethality: 2
  • Negative Genetic: 269
  • Phenotypic Enhancement: 5
  • Phenotypic Suppression: 3
  • Positive Genetic: 32
  • Synthetic Growth Defect: 228
  • Synthetic Lethality: 80
  • Synthetic Rescue: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 380
Molecular Weight (Da) 44,073
Isoelectric Point (pI) 6.45
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIII:95763 to 94621 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2006-01-12 | Sequence: 2000-09-13
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1143 95763..94621 2006-01-12 2000-09-13
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000521
References cited on this page View Complete Literature Guide for DCC1
1) Mayer ML, et al.  (2001) Identification of RFC(Ctf18p, Ctf8p, Dcc1p): an alternative RFC complex required for sister chromatid cohesion in S. cerevisiae. Mol Cell 7(5):959-70
2) Askree SH, et al.  (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63